Name: Pneumocandin B0
Brand: Creative Peptides
SKU: Z10-101-159
Availability: MadeToOrder

Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C50H80N8O17
M.W/Mr.	1065.2
Labeling Target	Beta-(1,3)-glucan synthase
Application	Pneumocandin B0 is a potent antifungal and inhibitor of Β-(1,3)-D-glucan synthesis.
Appearance	Solid powder
Purity	>98% (or refer to the Certificate of Analysis)
Biological Activity	Pneumocandin B0 is a lipohexapeptide composed of a 10R,12S-dimethylmyristoyl side chain and a hexapeptide core, which is produced by the fungus Glarea lozoyensis.
Areas of Interest	Immunology & Inflammation Cell Biology Cancer
Functions	A potent antifungal and inhibitor of ß-(1,3)-D-glucan synthesis

Long-term Storage Conditions	Soluble in DMSO
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions	Dry, dark and at 0 - 4 °C
Solubility	-20 °C
InChI	InChI=1S/C50H80N8O17/c1-5-25(2)20-26(3)12-10-8-6-7-9-11-13-37(66)52-31-22-35(64)46(71)56-48(73)41-33(62)18-19-57(41)50(75)39(34(63)23-36(51)65)54-47(72)40(43(68)42(67)28-14-16-29(60)17-15-28)55-45(70)32-21-30(61)24-58(32)49(74)38(27(4)59)53-44(31)69/h14-17,25-27,30-35,38-43,46,59-64,67-68,71H,5-13,18-24H2,1-4H3,(H2,51,65)(H,52,66)(H,53,69)(H,54,72)(H,55,70)(H,56,73)/t25?,26?,27-,30-,31+,32+,33+,34-,35-,38+,39+,40+,41+,42+,43+,46-/m1/s1
InChI Key	DQXPFAADCTZLNL-ZESADUFFSA-N
Isomeric SMILES	CCC(C)CC(C)CCCCCCCCC(=O)N[C@H]1C[C@H]([C@H](NC(=O)[C@@H]2[C@H](CCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@@H](NC1=O)[C@@H](C)O)O)[C@@H]([C@H](C4=CC=C(C=C4)O)O)O)[C@@H](CC(=O)N)O)O)O)O
BoilingPoint	1442.9±65.0 °C at 760 mmHg
ShelfLife	>2 years if stored properly
Melting Point	N/A

1. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists

2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

3. cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging

4. Sex differences in oxidative stress level and antioxidative enzymes expression and activity in obese pre-diabetic elderly rats treated with metformin or liraglutide

5. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

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