Puromycin aminonucleoside

Puromycin aminonucleoside is a puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring. It is an antibiotic with antineoplastic properties and can cause nephrosis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

Puromycin aminonucleoside(CAS 58-60-6)

CAT No: MFP-044

CAS No:58-60-6

Synonyms/Alias:Stylomycin aminonucleoside; 3'-amino-3'-deoxy-n6,n6-dimethyladenosine; 3'-Amino-3'-deoxy-N,N-dimethyladenosine

Chemical Name:(2R,3R,4S,5S)-4-amino-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolan-3-ol

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Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C12H18N6O3

M.W/Mr.

294.31

InChI

InChI=1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7-,9-,12-/m1/s1

InChI Key

RYSMHWILUNYBFW-GRIPGOBMSA-N

Canonical SMILES

CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)N)O

Isomeric SMILES

CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)N)O

1. The effect of B-type allatostatin neuropeptides on crosstalk between the insect immune response and cold tolerance

2. Implications of ligand-receptor binding kinetics on GLP-1R signalling

3. Therapeutic potential of an intestinotrophic hormone, glucagon-like peptide 2, for treatment of type 2 short bowel syndrome rats with intestinal bacterial and fungal dysbiosis

4. An Open-label, Single-center, Safety and Efficacy Study of Eyelash Polygrowth Factor Serum

5. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

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