Rapamycin is a macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production.
CAT# | Z10-101-156 |
CAS | 53123-88-9 |
Synonyms/Alias | Sirolimus; Rapamune; 53123-88-9; AY 22 989; I 2190A |
M.F/Formula | C51H79NO13 |
M.W/Mr. | 914.18 |
Labeling Target | Serine/threonine-protein kinase mTOR |
Application | Rapamycin is a potent immunosuppressant, and have both antifungal and antineoplastic properties. |
Appearance | White to off-white solid powder |
Purity | >98% (or refer to the Certificate of Analysis) |
Activity | Inhibitor |
Biological Activity | Rapamycin, a specific inhibitor of mTOR, has been shown to be useful in the treatment of certain diseases. |
Areas of Interest | Immunosuppressant; Lymphangioleiomyomatosis (LAM) |
Functions | Tfiiic-class transcription factor binding |
Disease | Carcinoma of breast; Renal cell carcinoma; Prevention of Kidney Transplant Rejection; Pancreatic Neuroendocrine Tumor |
Target | mTOR |
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