rh-Polypeptide-3 is a recombinant peptide produced via controlled biotechnological processes, designed for use in advanced cosmetic formulations. This ingredient is valued for its biomimetic structure, which supports the development of skin care products targeting the appearance of aging and compromised skin barrier function. rh-Polypeptide-3 is suitable for inclusion in serums, creams, and emulsions, offering formulators a stable and reproducible active for innovative cosmetic solutions.
Mechanism of Action (MOA)
rh-Polypeptide-3 is a recombinant bioactive peptide designed to mimic naturally occurring signaling sequences found in human skin. Upon topical application, it interacts with cell surface receptors, supporting cellular communication pathways such as MAPK and PI3K/Akt. This signaling may influence keratinocyte and fibroblast activity, contributing to the modulation of extracellular matrix components. rh-Polypeptide-3 is classified as a signaling peptide, facilitating intercellular dialogue that can support skin’s structural environment.
rh-Polypeptide-3 is suitable for incorporation into a variety of cosmetic formulations.
- Facial serums for daily skincare routines- Lightweight emulsions and creams- Eye contour products- Leave-on masks and overnight treatments- Sheet masks and hydrogel patches- Post-cleansing toners and essences- Targeted spot treatment formulas
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3. An Open-label, Single-center, Safety and Efficacy Study of Eyelash Polygrowth Factor Serum
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.