Rimtoregtide

Rimtoregtide features a tailored peptide architecture used in advanced receptor and signaling research. Distinct residue placement enables modeling of molecular recognition within regulatory pathways. Its physicochemical properties support analyses of conformational dynamics in solution. Investigators employ the compound in binding assays, sequence optimization, and bioactive peptide design.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Rimtoregtide(CAS 2251722-35-5)

CAT No: R2320

CAS No:2251722-35-5

Synonyms/Alias:Rimtoregtide;2251722-35-5;Rimtoregtide [INN];UNII-NYA2G8ZG88;NYA2G8ZG88;L-Serine, N-acetyl-L-isoleucylglycyl-L-leucyl-L-histidyl-L-alpha-aspartyl-L-prolyl-L-seryl-L-histidylglycyl-L-threonyl-L-leucyl-L-prolyl-L-alanylglycyl-;HTD4010;GLXC-27906;HY-P3377;DA-57452;MS-32190;CS-0376567;

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M.F/Formula
C65H101N19O22
M.W/Mr.
1500.6
Sequence
One Letter Code:IGLHDPSHGTLPAGS
Three Letter Code:Ac-Ile-Gly-Leu-His-Asp-Pro-Ser-His-Gly-Thr-Leu-Pro-Ala-Gly-Ser-OH

Rimtoregtide is a synthetic carbohydrate-based compound that has garnered significant attention in the scientific community due to its unique structural properties and versatile functional capabilities. As a member of the glycopeptide family, Rimtoregtide integrates the molecular complexity of carbohydrates with peptide frameworks, offering researchers a multifaceted tool for advancing biochemical and molecular studies. Its robust stability and tailored reactivity make it an excellent candidate for a variety of experimental protocols in both fundamental and applied sciences. The compound's distinctive architecture supports precise interactions with a range of biomolecules, allowing for targeted investigations into cellular processes, molecular recognition, and advanced material development. Researchers value Rimtoregtide for its reproducibility and adaptability across diverse laboratory settings, where it serves as a pivotal component in expanding the frontiers of carbohydrate chemistry and peptide research.

Glycobiology Research: Rimtoregtide is extensively used in glycobiology research to probe the interactions between carbohydrates and proteins, elucidating the roles of glycan structures in cellular communication and signaling pathways. By incorporating this compound into model systems, scientists can closely examine how specific glycan motifs influence protein folding, stability, and function. Its synthetic nature allows for the systematic modification of carbohydrate moieties, enabling detailed structure-activity relationship studies that are essential for understanding complex biological mechanisms. As a result, Rimtoregtide facilitates the discovery of novel glycan-binding proteins and helps decode the functional significance of carbohydrate modifications in health and disease.

Drug Discovery and Development: Rimtoregtide serves as a valuable scaffold in the early stages of drug discovery, particularly for the design of glycopeptide-based therapeutics and molecular probes. Its modular structure allows medicinal chemists to attach various functional groups, tailoring molecular recognition properties for specific biological targets. By mimicking natural glycopeptide structures, Rimtoregtide-based analogs can be screened for their ability to modulate key biochemical pathways, inhibit pathogenic enzymes, or block undesirable protein-protein interactions. This approach accelerates the identification of promising lead compounds and enhances the efficiency of medicinal chemistry campaigns focused on carbohydrate-related targets.

Biomaterials Engineering: In the field of biomaterials engineering, Rimtoregtide plays an instrumental role in the development of novel materials with enhanced biocompatibility and functionality. Its carbohydrate-peptide hybrid structure provides a versatile foundation for constructing hydrogels, scaffolds, and coatings that support cell adhesion, proliferation, and differentiation. Researchers utilize Rimtoregtide to impart specific bioactive cues to materials, promoting desirable cellular responses in tissue engineering and regenerative medicine contexts. Moreover, its chemical versatility enables the fine-tuning of mechanical and biological properties, leading to the creation of customized biomaterials for a variety of biomedical applications.

Analytical and Diagnostic Tools: The unique binding properties of Rimtoregtide make it an excellent candidate for the development of analytical and diagnostic tools. Scientists employ it as a molecular probe or capture agent in biosensor platforms to selectively detect glycan-binding proteins, lectins, or other carbohydrate-interacting molecules. Its synthetic origin ensures batch-to-batch consistency, which is critical for the reproducibility of diagnostic assays. By integrating Rimtoregtide into microarrays, chromatography columns, or surface plasmon resonance systems, researchers can achieve high sensitivity and specificity in the detection and quantification of biologically relevant analytes, supporting advances in biomarker discovery and disease monitoring.

Enzymology Studies: Rimtoregtide is utilized in enzymology studies to investigate the specificity and catalytic mechanisms of glycosyltransferases, glycosidases, and other carbohydrate-processing enzymes. By serving as a defined substrate or inhibitor, it enables the detailed characterization of enzyme kinetics, substrate preferences, and reaction mechanisms. The controlled presentation of carbohydrate motifs on Rimtoregtide allows researchers to dissect the molecular determinants of enzyme-substrate recognition, providing insights that are fundamental to enzyme engineering and the development of novel biocatalysts. This application is particularly valuable for advancing our understanding of carbohydrate metabolism and the design of enzyme-based technologies for industrial and research purposes.

InChI
InChI=1S/C65H101N19O22/c1-10-33(6)52(74-36(9)88)61(101)70-25-48(89)75-39(17-31(2)3)56(96)78-41(20-38-23-67-30-72-38)57(97)79-43(21-51(92)93)64(104)84-16-12-14-47(84)60(100)81-44(27-85)58(98)77-40(19-37-22-66-29-71-37)55(95)69-26-50(91)82-53(35(8)87)62(102)80-42(18-32(4)5)63(103)83-15-11-13-46(83)59(99)73-34(7)54(94)68-24-49(90)76-45(28-86)65(105)106/h22-23,29-35,39-47,52-53,85-87H,10-21,24-28H2,1-9H3,(H,66,71)(H,67,72)(H,68,94)(H,69,95)(H,70,101)(H,73,99)(H,74,88)(H,75,89)(H,76,90)(H,77,98)(H,78,96)(H,79,97)(H,80,102)(H,81,100)(H,82,91)(H,92,93)(H,105,106)/t33-,34-,35+,39-,40-,41-,42-,43-,44-,45-,46-,47-,52-,53-/m0/s1
InChI Key
PAVULCXCHYUXAY-NTUCKVCISA-N

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