SHLP4 (Small humanin-like peptide 4)

Name: SHLP4 (Small humanin-like peptide 4)
Brand: Creative Peptides
SKU: X21191
Availability: MadeToOrder

Recent advances in high-resolution sequencing have led to the discovery of unique peptides derived from mitochondrial genome. 1-2 Currently 8 peptides are identified: humanin, mitochondrial open reading frame of the 12S tRNA-c (MOTS-c), and six small humanin-like peptides (SHLP1-6). 1-2 All of these peptides are released into cytosol from mitochondria. SHLP4 may promote cell proliferation in certain cells and could be involved in reduced apoptosis. 1-2

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X21191

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

3131.85

Sequence

One Letter Code: H-MLEVMFLVNRRGKICRVPFTFFNLSL-OH
Three Letter Code: NH2-Met-Leu-Glu-Val-Met-Phe-Leu-Val-Asn-Arg-Arg-Gly-Lys-Ile-Cys-Arg-Val-Pro-Phe-Thr-Phe-Phe-Asn-Leu-Ser-Leu-COOH

References

1. Cobb L. J. et al., AGING 8 (4), 796-808 (2016).
2. Okada A. K. et al., Sci Reports 7 (7802), 1-10 (2017). .

1. A possible role of tachykinin-related peptide on an immune system activity of mealworm beetle, Tenebrio molitor L

2. Crystal Structure of BamB from Pseudomonas aeruginosa and Functional Evaluation of Its Conserved Structural Features

3. Implications of ligand-receptor binding kinetics on GLP-1R signalling

4. Emerging applications of nanotechnology for diagnosis and therapy of disease: a review

5. TMEM16F and dynamins control expansive plasma membrane reservoirs

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