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Substance P (1-7)

Substance P (SP) is an endogenous tachykinin neuropeptide that is involved in inflammatory, pain, and stress signaling; it exhibits neuroprotective, cognition-enhancing, and gastrointestinal motility modulating activities. SP is the natural ligand for the neurokinin-1 (NK1) receptor.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R1875

CAS No:68060-49-1

Synonyms/Alias:68060-49-1;Substance P (1-7);2-[[5-amino-2-[[5-amino-2-[[1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoic acid;H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-OH;Substance P 1-7;DTXSID30391872;AKOS037645190;AS-58201;PD087830;G77863;2-[2-(2-{[1-(6-AMINO-2-{[1-(2-AMINO-5-CARBAMIMIDAMIDOPENTANOYL)PYRROLIDIN-2-YL]FORMAMIDO}HEXANOYL)PYRROLIDIN-2-YL]FORMAMIDO}-4-CARBAMOYLBUTANAMIDO)-4-CARBAMOYLBUTANAMIDO]-3-PHENYLPROPANOIC ACID;

Chemical Name:2-[[5-amino-2-[[5-amino-2-[[1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C41H65N13O10
M.W/Mr.
900
Sequence
One Letter Code:RPKPQQF
Three Letter Code:H-DL-Arg-DL-Pro-DL-Lys-DL-Pro-DL-Gln-DL-Gln-DL-Phe-OH
Purity
≥97% (HPLC)
Length
7
Long-term Storage Conditions
10 mM in H2O
Shipping Condition
Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
InChI
InChI=1S/C41H65N13O10/c42-19-5-4-12-28(51-37(60)30-13-7-21-53(30)38(61)25(43)11-6-20-48-41(46)47)39(62)54-22-8-14-31(54)36(59)50-27(16-18-33(45)56)34(57)49-26(15-17-32(44)55)35(58)52-29(40(63)64)23-24-9-2-1-3-10-24/h1-3,9-10,25-31H,4-8,11-23,42-43H2,(H2,44,55)(H2,45,56)(H,49,57)(H,50,59)(H,51,60)(H,52,58)(H,63,64)(H4,46,47,48)
InChI Key
KPHDBQWTCKBKIL-UHFFFAOYSA-N
Canonical SMILES
C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)O

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