Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate of calpains and 20S proteasome and used to study the activity of calpains and proteosomal degradation. It is also a substrate for carboxypeptidase Y, proteinase yscE (kexin), ingensin, as well as for porcine calpain isozymes I and II and for papain.
CAT No: R0808
CAS No:94367-21-2
Synonyms/Alias:Suc-Leu-Leu-Val-Tyr-AMC;94367-21-2;Suc-leu-leu-val-tyr-mca;Suc-llvy-mca;Suc-LLVY-AMC;Sllvt-mca;Llvy-mca;S6510_SIGMA;N-Succinyl-leu-leu-val-tyr-7-amido-4-methylcoumarin;7GVY2DYZ80;succinyl-leucyl-leucyl-valyl-tyrosyl-methylcoumarinamide;Suc-leu-leu-val-tyr-7-amino-4-methylcoumarin;MFCD00080248;UNII-7GVY2DYZ80;succinyl-Leu-Leu-Val-Tyr-7-amino-4-methylcoumarin;CHEBI:52770;4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-3-(4-hydroxyphenyl)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid;4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-3-(4-hydroxyphenyl)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl] amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid;N-(3-carboxypropanoyl)-L-leucyl-L-leucyl-L-valyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-tyrosinamide;succinyl-Leu-Leu-Val-Tyr-MCA;L-Tyrosinamide, N-(3-carboxy-1-oxopropyl)-L-leucyl-L-leucyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;succinyl-Leu-Leu-Val-Tyr-4-methylcoumaryl-7-amide;succinyl-Leu-Leu-Val-Tyr-4-methyl-coumaryl-7-amide;2: PN: US20060073535 PAGE: 8 claimed protein; 3: PN: US20080138837 PAGE: 9 claimed protein; 4: PN: WO0197794 SEQID: 33 claimed protein; N-(3-Carboxy-1-oxopropyl)-L-leucyl-L-leucyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tyrosinamide;4-(((2S)-1-(((2S)-1-(((2S)-1-(((2S)-3-(4-hydroxyphenyl)-1-((4-methyl-2-oxochromen-7-yl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl) amino)-4-methyl-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-4-oxobutanoic acid;SCHEMBL4755762;N-succinyl-Leu-Leu-Val-Tyr-AMC;UVFAEQZFLBGVRM-MSMWPWNWSA-N;HY-P1002;CS-7678;Suc-LLVY-AMC, Proteasome substrate (fluorogenic), Calpain substrate (fluorogenic);DA-78085;FS110535;MS-31369;Suc-Leu-Leu-Val-Tyr-4-methyl-7-coumarylamide;N-succinyl-Leu-Leu-Val-Tyr-4-methyl-7-coumarylamide;Q27123591;(2S,5S,8S,11S)-2-(4-hydroxybenzyl)-8,11-diisobutyl-5-isopropyl-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1,4,7,10,13-pentaoxo-3,6,9,12-tetraazahexadecan-16-oic acid;L-Tyrosinamide,N-(3-carboxy-1-oxopropyl)-L-leucyl-L-leucyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;
3. Cationic cell-penetrating peptides are potent furin inhibitors
4. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
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