Suc-Leu-Leu-Val-Tyr-AMC

Name: Suc-Leu-Leu-Val-Tyr-AMC
Brand: Creative Peptides
SKU: R0808
Availability: MadeToOrder

Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate of calpains and 20S proteasome and used to study the activity of calpains and proteosomal degradation. It is also a substrate for carboxypeptidase Y, proteinase yscE (kexin), ingensin, as well as for porcine calpain isozymes I and II and for papain.

Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

CAT No: R0808

CAS No: 94367-21-2

Synonyms/Alias: Suc-Leu-Leu-Val-Tyr-AMC;94367-21-2;Suc-leu-leu-val-tyr-mca;Suc-llvy-mca;Suc-LLVY-AMC;Sllvt-mca;Llvy-mca;S6510_SIGMA;N-Succinyl-leu-leu-val-tyr-7-amido-4-methylcoumarin;7GVY2DYZ80;succinyl-leucyl-leucyl-valyl-tyrosyl-methylcoumarinamide;Suc-leu-leu-val-tyr-7-amino-4-methylcoumarin;MFCD00080248;UNII-7GVY2DYZ80;succinyl-Leu-Leu-Val-Tyr-7-amino-4-methylcoumarin;CHEBI:52770;4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-3-(4-hydroxyphenyl)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid;4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-3-(4-hydroxyphenyl)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl] amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid;N-(3-carboxypropanoyl)-L-leucyl-L-leucyl-L-valyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-tyrosinamide;succinyl-Leu-Leu-Val-Tyr-MCA;L-Tyrosinamide, N-(3-carboxy-1-oxopropyl)-L-leucyl-L-leucyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;succinyl-Leu-Leu-Val-Tyr-4-methylcoumaryl-7-amide;succinyl-Leu-Leu-Val-Tyr-4-methyl-coumaryl-7-amide;2: PN: US20060073535 PAGE: 8 claimed protein; 3: PN: US20080138837 PAGE: 9 claimed protein; 4: PN: WO0197794 SEQID: 33 claimed protein; N-(3-Carboxy-1-oxopropyl)-L-leucyl-L-leucyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tyrosinamide;4-(((2S)-1-(((2S)-1-(((2S)-1-(((2S)-3-(4-hydroxyphenyl)-1-((4-methyl-2-oxochromen-7-yl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl) amino)-4-methyl-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-4-oxobutanoic acid;SCHEMBL4755762;N-succinyl-Leu-Leu-Val-Tyr-AMC;UVFAEQZFLBGVRM-MSMWPWNWSA-N;HY-P1002;CS-7678;Suc-LLVY-AMC, Proteasome substrate (fluorogenic), Calpain substrate (fluorogenic);DA-78085;FS110535;MS-31369;Suc-Leu-Leu-Val-Tyr-4-methyl-7-coumarylamide;N-succinyl-Leu-Leu-Val-Tyr-4-methyl-7-coumarylamide;Q27123591;(2S,5S,8S,11S)-2-(4-hydroxybenzyl)-8,11-diisobutyl-5-isopropyl-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1,4,7,10,13-pentaoxo-3,6,9,12-tetraazahexadecan-16-oic acid;L-Tyrosinamide,N-(3-carboxy-1-oxopropyl)-L-leucyl-L-leucyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C40H53N5O10
M.W/Mr.	763.9
Sequence	One Letter Code:LLVY Three Letter Code:Suc-Leu-Leu-Val-Tyr-AMC
Application	A fluorgenic substrate
Purity	> 97%
Areas of Interest	Cell Biology

Source#	Synthetic
Long-term Storage Conditions	Soluble in DMSO
Solubility	-20 °C
InChI	InChI=1S/C40H53N5O10/c1-21(2)16-29(42-33(47)14-15-34(48)49)38(52)43-30(17-22(3)4)39(53)45-36(23(5)6)40(54)44-31(19-25-8-11-27(46)12-9-25)37(51)41-26-10-13-28-24(7)18-35(50)55-32(28)20-26/h8-13,18,20-23,29-31,36,46H,14-17,19H2,1-7H3,(H,41,51)(H,42,47)(H,43,52)(H,44,54)(H,45,53)(H,48,49)/t29-,30-,31-,36-/m0/s1
InChI Key	UVFAEQZFLBGVRM-MSMWPWNWSA-N
Isomeric SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)CCC(=O)O
BoilingPoint	1116.8ºC at 760mmHg
Melting Point	N/A

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