Suc-Leu-Leu-Val-Tyr-AMC

Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate of calpains and 20S proteasome and used to study the activity of calpains and proteosomal degradation. It is also a substrate for carboxypeptidase Y, proteinase yscE (kexin), ingensin, as well as for porcine calpain isozymes I and II and for papain.

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CAT#	R0808
CAS	94367-21-2
Synonyms/Alias	Suc-LLVY-AMC, Proteasome substrate (fluorogenic), Calpain substrate (fluorogenic)
M.F/Formula	C40H53N5O10
M.W/Mr.	763.89
Sequence	Suc-Leu-Leu-Val-Tyr-AMC
Application	A fluorgenic substrate
Purity	> 97%
Areas of Interest	Cell Biology

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Source#	Synthetic
Storage	-20°C
Solubility	Soluble in DMSO
Long-term Storage Conditions	-20 °C
InChI	InChI=1S/C40H53N5O10/c1-21(2)16-29(42-33(47)14-15-34(48)49)38(52)43-30(17-22(3)4)39(53)45-36(23(5)6)40(54)44-31(19-25-8-11-27(46)12-9-25)37(51)41-26-10-13-28-24(7)18-35(50)55-32(28)20-26/h8-13,18,20-23,29-31,36,46H,14-17,19H2,1-7H3,(H,41,51)(H,42,47)(H,43,52)(H,44,54)(H,45,53)(H,48,49)/t29-,30-,31-,36-/m0/s1
InChI Key	UVFAEQZFLBGVRM-MSMWPWNWSA-N
Isomeric SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)CCC(=O)O
BoilingPoint	1116.8ºC at 760mmHg
Melting Point	N/A