Z-Asn(Mtt)-OH contains an asparagine amino acid core bearing a side-chain carboxamide, with the alpha-amino group protected as a Z (benzyloxycarbonyl) carbamate and the side-chain amide substituted with an Mtt (4-methyltrityl) protecting group. The molecule therefore presents a free carboxylic acid (-COOH) while the -NH2 functionalities are masked by orthogonally removable protecting groups, and its substitution pattern supports controlled chemoselectivity during stepwise peptide assembly. Z-Asn(Mtt)-OH is used as a protected amino acid building block for peptide synthesis and related peptide-derivative preparation, where orthogonal deprotection of the Mtt and Z groups enables selective unveiling of the side-chain and N-terminus for subsequent coupling or functionalization.
CAT No: CP26385
CAS No:144317-18-0
Synonyms/Alias:144317-18-0;(S)-2-(((Benzyloxy)carbonyl)amino)-4-((diphenyl(p-tolyl)methyl)amino)-4-oxobutanoicacid;ZINC15721663;AKOS015909212;AJ-67833;AK142169;I14-33067;L-Asparagine,N-[(4-methylphenyl)diphenylmethyl]-N2-[(phenylmethoxy)carbonyl]-(9CI)
1. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
2. Emu oil in combination with other active ingredients for treating skin imperfections
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