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Z-Asn(Mtt)-OH

Z-Asn(Mtt)-OH contains an asparagine amino acid core bearing a side-chain carboxamide, with the alpha-amino group protected as a Z (benzyloxycarbonyl) carbamate and the side-chain amide substituted with an Mtt (4-methyltrityl) protecting group. The molecule therefore presents a free carboxylic acid (-COOH) while the -NH2 functionalities are masked by orthogonally removable protecting groups, and its substitution pattern supports controlled chemoselectivity during stepwise peptide assembly. Z-Asn(Mtt)-OH is used as a protected amino acid building block for peptide synthesis and related peptide-derivative preparation, where orthogonal deprotection of the Mtt and Z groups enables selective unveiling of the side-chain and N-terminus for subsequent coupling or functionalization.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26385

CAS No:144317-18-0

Synonyms/Alias:144317-18-0;(S)-2-(((Benzyloxy)carbonyl)amino)-4-((diphenyl(p-tolyl)methyl)amino)-4-oxobutanoicacid;ZINC15721663;AKOS015909212;AJ-67833;AK142169;I14-33067;L-Asparagine,N-[(4-methylphenyl)diphenylmethyl]-N2-[(phenylmethoxy)carbonyl]-(9CI)

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M.F/Formula
C32H30N2O5
M.W/Mr.
522.6
Size
5 g;25 g;
InChI
1S/C32H30N2O5/c1-23-17-19-27(20-18-23)32(25-13-7-3-8-14-25,26-15-9-4-10-16-26)34-29(35)21-28(30(36)37)33-31(38)39-22-24-11-5-2-6-12-24/h2-20,28H,21-22H2,1H3,(H,33,38)(H,34,35)(H,36,37)/t28-/m0/s1
InChI Key
OOWKUTRZJDOGPF-NDEPHWFRSA-N
Canonical SMILES
CC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)CC(C(=O)O)NC(=O)OCC4=CC=CC=C4

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