Z-D-Ala-OSu is a protected D-alanine derivative in which the amino group is carbamated with a benzyloxycarbonyl (Z, Cbz) protecting group and the carboxyl functionality is converted to an N-hydroxysuccinimide (OSu) ester. The molecule contains a Z-protected amino group and a carboxyl-derived OSu ester, with stereochemistry specified as D at the alanine center and a side chain consisting of a methyl group, while the OSu ester bears a leaving group suited to acyl transfer chemistry. Z-D-Ala-OSu is used in peptide and amide bond synthesis as an activated amino acid acylating agent, and it also serves as a reagent for preparing labeled or conjugated alanine-containing derivatives under conditions that promote nucleophilic acyl substitution.
CAT No: CP26930
CAS No:27167-53-9
Synonyms/Alias:Z-D-Ala-OSu;27167-53-9;AC1LHGYH;SCHEMBL10345811;CTK8G3817;MolPort-020-004-595;ZINC365049;Z-D-alanine-N-hydroxysuccinimideester;AK-81316;K-6940;(2,5-dioxopyrrolidin-1-yl)(2R)-2-(phenylmethoxycarbonylamino)propanoate;1-[(R)-1-Oxo-2-[[(benzyloxy)carbonyl]amino]propoxy]-2,5-pyrrolidinedione;D-Alanine,N-[(phenylmethoxy)carbonyl]-,2,5-dioxo-1-pyrrolidinylester
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