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Z-D-Thr-OH

Z-D-Thr-OH contains the amino acid framework of threonine with a benzyl-type carbamate protecting group on the amino functionality (Z, i.e., Cbz) and a free carboxylic acid (OH), forming a protected D-threonine derivative. The side chain includes a hydroxyl-bearing aliphatic group that provides polarity and hydrogen-bonding capability, while the stereochemical designation "D" specifies the configuration at the α-carbon and the molecule retains both the protected amine and carboxyl functional groups for controlled reactivity. Z-D-Thr-OH is used as a stepwise peptide synthesis building block where the Cbz-protected amino group supports chemoselective coupling chemistry and the free carboxylic acid enables incorporation into peptide-related intermediates or analytical derivatization workflows.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP27495

CAS No:80384-27-6

Synonyms/Alias:Z-D-Thr-OH;80384-27-6;Z-D-threonine;N-Carbobenzoxy-D-threonine;(2R,3S)-2-(((Benzyloxy)carbonyl)amino)-3-hydroxybutanoicacid;N-Cbz-D-threonine;N-BENZYLOXYCARBONYL-D-THREONINE;(2R,3S)-3-hydroxy-2-(phenylmethoxycarbonylamino)butanoicacid;Cbz-D-Thr-OH;AC1LGXJI;CBZ-D-THREONINE;PHQ-DTH;SCHEMBL6389671;97225_FLUKA;MolPort-003-939-987;ZINC392036;KM2030;MFCD00037808;AKOS015836906;AB01667;N-ALPHA-CARBOBENZOXY-D-THREONINE;AJ-21223;AK111191;C2138;ST24034005

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C12H15NO5
M.W/Mr.
253.26
Size
1 g;5 g;25 g;
InChI
1S/C12H15NO5/c1-8(14)10(11(15)16)13-12(17)18-7-9-5-3-2-4-6-9/h2-6,8,10,14H,7H2,1H3,(H,13,17)(H,15,16)/t8-,10+/m0/s1
InChI Key
IPJUIRDNBFZGQN-WCBMZHEXSA-N
Canonical SMILES
CC(C(C(=O)O)NC(=O)OCC1=CC=CC=C1)O

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