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Z-Gly-Pro-Arg-AMC HCl

Z-Gly-Pro-Arg-AMC HCl combines a protected peptide motif with an AMC fluorophore to support detection of proteolytic activity. Glycine and proline shape turn formation, while arginine provides strong electrostatic interactions. Researchers evaluate its cleavage kinetics and fluorescence behavior. Applications include enzyme assays, substrate optimization, and mechanistic studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Z-Gly-Pro-Arg-AMC HCl(CAS 201928-42-9)

CAT No: R2476

CAS No:201928-42-9

Synonyms/Alias:201928-42-9;Z-Gly-Pro-Arg-AMC HCl;Z-Gly-Pro-Arg-AMC.HCl;Z-Gly-Pro-Arg-AMC (hydrochloride);Z-Gly-Pro-Arg-Mca Hydrochloride;benzyl N-[2-[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]carbamate;hydrochloride;Z-Gly-pro-arg-amc hydrochloride;WIIZWHSOXXZHRC-UKOKCHKQSA-N;HY-P4217;MFCD00077020;FG110494;CS-0650897;Benzyl (2-((S)-2-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-2-oxoethyl)carbamate hydrochloride;benzyl 2-((S)-2-((S)-5-guanidino-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopentan-2-ylcarbamoyl)pyrrolidin-1-yl)-2-oxoethylcarbamate hydrochloride;BENZYL N-{2-[(2S)-2-{[(1S)-4-CARBAMIMIDAMIDO-1-[(4-METHYL-2-OXOCHROMEN-7-YL)CARBAMOYL]BUTYL]CARBAMOYL}PYRROLIDIN-1-YL]-2-OXOETHYL}CARBAMATE HYDROCHLORIDE;L-Argininamide,N-[(phenylmethoxy)carbonyl]glycyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-,monohydrochloride(9ci);

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C31H38ClN7O7
M.W/Mr.
656.1
Sequence
One Letter Code:GPR
Three Letter Code:Cbz-Gly-Pro-Arg-AMC.HCl
InChI
InChI=1S/C31H37N7O7.ClH/c1-19-15-27(40)45-25-16-21(11-12-22(19)25)36-28(41)23(9-5-13-34-30(32)33)37-29(42)24-10-6-14-38(24)26(39)17-35-31(43)44-18-20-7-3-2-4-8-20;/h2-4,7-8,11-12,15-16,23-24H,5-6,9-10,13-14,17-18H2,1H3,(H,35,43)(H,36,41)(H,37,42)(H4,32,33,34);1H/t23-,24-;/m0./s1
InChI Key
WIIZWHSOXXZHRC-UKOKCHKQSA-N

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