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Z-L-cis-Hyp-OH

Z-L-cis-Hyp-OH contains the amino acid hydroxyproline (Hyp) in a cis ring conformation, with the L stereochemical designation and a Z-configured substituent as indicated by the product name. The molecule bears a free carboxylic acid (-COOH) and an amino group (-NH2) while featuring the characteristic β-hydroxyl side chain of hydroxyproline that can participate in hydrogen bonding and influence peptide conformational preferences. As a free, stereochemically specified amino acid building block, it is used in peptide synthesis and structure-conformation studies where cis-hydroxyproline geometry and side-chain functionality are required for preparing hydroxyproline-containing peptide analogues and related derivatives.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25323

CAS No:13504-86-4

Synonyms/Alias:13504-86-4;(2S,4S)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylicacid;(2S,4S)-1-((Benzyloxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylicacid;Z-CIS-HYP-OH;130930-25-5;(2S,4S)-N-CARBOBENZYLOXY-4-HYDROXY-L-PROLINE;(2S,4S)-1-[(benzyloxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylicacid;(2S,4S)-4-HYDROXY-1,2-PYRROLIDINEDICARBOXYLICACID1-(PHENYLMETHYL)ESTER;Z-D-CIS-HYP-OH;AmbotzZAA1179;CIS-ZHPRO;Z-CIS-L-HYP-OH;Z-L-CIS-HYP-OH;AC1LEM15;SCHEMBL71528;CTK8C5125;Z-L-CIS-4-HYDROXYPROLINE;MolPort-008-269-439;WWVCWLBEARZMAH-QWRGUYRKSA-N;Z-CIS-4-HYDROXY-L-PROLINE;13504-85-3;ZINC4743912;CBZ-CIS-4-HYDROXY-L-PROLINE;ANW-74252;AKOS014040349

Chemical Name:cis-N-alpha-Benzyloxycarbonyl-L-hydroxyproline, (2S,4S)-N-Benzyloxycarbonyl-4-hydroxy-2-pyrrolinecarboxylic acid

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
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M.F/Formula
C13H15NO5
M.W/Mr.
265,27 g/mole
Size
1 g;5 g;
InChI
1S/C13H15NO5/c15-10-6-11(12(16)17)14(7-10)13(18)19-8-9-4-2-1-3-5-9/h1-5,10-11,15H,6-8H2,(H,16,17)/t10-,11-/m0/s1
InChI Key
WWVCWLBEARZMAH-QWRGUYRKSA-N
Canonical SMILES
C1C(CN(C1C(=O)O)C(=O)OCC2=CC=CC=C2)O

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