Z-L-Dbu(Fmoc)-OH is an Fmoc-protected amino acid derivative in which the amino acid backbone is linked to a Dbu side chain and carries a Z (benzyloxycarbonyl) protecting group on the amino function, with the "L" stereochemical designation specified in the name. The molecule contains a free carboxylic acid (-COOH) while the side-chain substituent and protected amine are rendered nonreactive under conditions used for stepwise peptide assembly, and the Fmoc group provides orthogonal protection that can be removed under deprotection conditions compatible with peptide synthesis. In synthetic workflows, it is employed as a protected building block for solid-phase or solution-phase peptide synthesis and for preparing peptide intermediates where controlled chemoselectivity and sequential incorporation of the Dbu-containing residue are required.
CAT No: CP25788
CAS No:349547-09-7
Synonyms/Alias:Z-beta-Dab(Fmoc)-OH;Z-beta-Dbu(Fmoc)-OH;(R)-4-(Fmoc-amino)-3-(Z-amino)butyricacid;349547-09-7;beta-Z-gamma-Fmoc-L-3,4-diaminobutyricacid;gamma-Fmoc-beta-Z-L-3,4-diaminobutyricacid;AmbotzZAA1056;Z-|A-Dab(Fmoc)-OH;Z-|A-Dbu(Fmoc)-OH;21622_ALDRICH;21622_FLUKA;MolPort-003-927-926;ZINC33438915
Chemical Name:(R)-N-beta-Benzyloxycarbonyl-N-gamma-(9-fluorenylmethyloxycarbonyl)-L-3,4-diaminobutyric acid
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