Z-L-Pro-ONp

Z-L-Pro-ONp is a protected amino acid derivative consisting of L-proline bearing an N-benzyloxycarbonyl (Z, Cbz) protecting group and an ONp ester at the carboxylate, forming a proline-based amino acid ONp ester. The molecule contains a carbamate-protected amino functionality and a carboxylate ester linkage to the p-nitrophenyl (ONp) leaving group, with stereochemistry consistent with the L-proline configuration indicated in the name. Z-L-Pro-ONp is used as an activated proline building block in peptide synthesis and related coupling workflows, where the ONp ester can participate in acyl transfer chemistry to assemble peptide bonds under appropriate conditions.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25756

CAS No:3304-59-4

Synonyms/Alias:Z-Pro-ONp;3304-59-4;(S)-1-Benzyl2-(4-nitrophenyl)pyrrolidine-1,2-dicarboxylate;ST50409578;benzyloxycarbonyl-l-proline4-nitrophenylester;3304-54-9;Z-L-Pro-ONp;C4877_SIGMA;SCHEMBL4613447;CTK8G3869;GXUFIJVKXYWCAO-KRWDZBQOSA-N;MolPort-003-910-290;ZINC4578893;N-Cbz-L-Prolinep-nitrophenylester;N-CBZ-L-proline4-nitrophenylester;AKOS016003309;VZ31396;AK-81337;KB-251023;FT-0634770;ST24032088;BENZYLXOYCARBONYL-L-PROLINE4-NITROPHENYLESTER;1-[(Phenylmethoxy)carbonyl]-L-proline4-nitrophenylester;1-benzyl2-(4-nitrophenyl)(2S)-pyrrolidine-1,2-dicarboxylate;phenylmethyl(2S)-2-[(4-nitrophenyl)oxycarbonyl]pyrrolidinecarboxylate

Chemical Name:N-alpha-Benzyloxycarbonyl-L-proline p-nitrophenyl ester

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C19H18N2O6
M.W/Mr.
370,35 g/mole
Size
5 g;25 g;
InChI
1S/C19H18N2O6/c22-18(27-16-10-8-15(9-11-16)21(24)25)17-7-4-12-20(17)19(23)26-13-14-5-2-1-3-6-14/h1-3,5-6,8-11,17H,4,7,12-13H2/t17-/m0/s1
InChI Key
GXUFIJVKXYWCAO-KRWDZBQOSA-N
Canonical SMILES
C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)OC3=CC=C(C=C3)[N+](=O)[O-]

Useful Tools

Peptide Calculator

Abbreviation List

Peptide Glossary

If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.

Featured Services
Epitope Mapping ServicesPeptide Modification ServicesPeptide Analysis ServicesPeptide Synthesis ServicesPeptide CDMOPeptide Nucleic Acids SynthesisCustom Conjugation ServicecGMP Peptide Service
Hot Products
About us

Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

Our Customers

Creative Peptides customer logo 1 Creative Peptides customer logo 2 Creative Peptides customer logo 3 Creative Peptides customer logo 4 Creative Peptides customer logo 5 Creative Peptides customer logo 6 Creative Peptides customer logo 7 Creative Peptides customer logo 8 Creative Peptides customer logo 9 Creative Peptides customer logo 10 Creative Peptides customer logo 11 Creative Peptides customer logo 12 Creative Peptides customer logo 13 Creative Peptides customer logo 14 Creative Peptides customer logo 15 Creative Peptides customer logo 16 Creative Peptides customer logo 17 Creative Peptides customer logo 18 Creative Peptides customer logo 19 Creative Peptides customer logo 20 Creative Peptides customer logo 21 Creative Peptides customer logo 22 Creative Peptides customer logo 23 Creative Peptides customer logo 24 Creative Peptides client partner 1 Creative Peptides client partner 2 Creative Peptides client partner 3 Creative Peptides client partner 4 Creative Peptides client partner 5 Creative Peptides client partner 6 Creative Peptides client partner 7 Creative Peptides client partner 8 Creative Peptides client partner 9 Creative Peptides client partner 10 Creative Peptides client partner 11 Creative Peptides client partner 12 Creative Peptides client partner 13 Creative Peptides client partner 14 Creative Peptides client partner 15 Creative Peptides client partner 16 Creative Peptides client partner 17 Creative Peptides client partner 18 Creative Peptides client partner 19 Creative Peptides client partner 20 Creative Peptides client partner 21 Creative Peptides client partner 22 Creative Peptides client partner 23 Creative Peptides client partner 24