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Liraglutide

Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Liraglutide(CAS 204656-20-2)

CAT No: 10-101-59

CAS No:204656-20-2

Synonyms/Alias:Liraglutide;204656-20-2;NN2211;victoza;Liraglutida;NN-2211;Liraglutidum;NN 2211;Liraglutidum [INN-Latin];Liraglutida [INN-Spanish];NNC 90-1170;UNII-839I73S42A;HSDB 8205;Liraglutide (rDNA origin);NNC-90-1170;CHEMBL4084119;Saxenda;CHEBI:71193;DTXSID60174433;839I73S42A;NN-9924;N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)GLP-1-(7-37)-peptide;Liraglutidum (INN-Latin);Liraglutida (INN-Spanish);N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)glucagon-like-peptide-1-(7-37)-peptide;Arg34Lys26-(N-epsilon-(gamma-Glu(N-alpha-hexadecanoyl)))-GLP-1(7-37);N(sup 26)-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)GLP-1-(7-37)-peptide;Liraglutide recombinant;Liraglutide?;L-Histidyl-L-alanyl-L-a-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-a-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-a-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-?-glutamyl]-L-lysyl-L-a-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine;Liraglutide [USAN:INN:BAN:JAN];Liraglutidum (Latin);LIRAGLUTIDE (MART.);GTPL1133;DTXCID6096924;A10BJ02;EX-A2418;BDBM50240819;NN9924;AKOS037435224;AS-56276;DA-65005;FL109949;XULTOPHY 100/3.6 COMPONENT LIRAGLUTIDE;LIRAGLUTIDE COMPONENT OF XULTOPHY 100/3.6;NN2211; (Lys(?-Glu-palmitoyl)(2)?,Arg(3)?)-GLP-1 (7-37);ARG(SUP 34)LYS(SUP 26)-(N-epsilon-(gamma-GLU(N-alpha-HEXADECANOYL)))-GLP-1(7-37);N(SUP epsilon26)-(N-HEXADECANOYL-L-gamma-GLUTAMYL)-(34-L-ARGININE)GLUCAGON-LIKE PEPTIDE 1-(7-37)-PEPTIDE;N26-(N-Hexadecanoyl-L-gamma-glutamyl)-(34-L-arginine)glucagon-like peptide 1-(7-37)-peptide;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C172H265N43O51
M.W/Mr.
3751
Sequence
Three Letter Code:H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(1)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH.palmitoyl-Glu(1)-OH
Long-term Storage Conditions
H2O : 5 mg/mL (1.33 mM; ultrasonic and adjust pH to 8 with NaOH)
Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C172H265N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-129(224)195-116(170(265)266)59-64-128(223)180-68-41-40-50-111(153(248)199-115(62-67-135(232)233)154(249)204-120(73-100-44-33-31-34-45-100)159(254)214-140(93(11)19-2)167(262)192-97(15)146(241)201-122(76-103-79-183-108-49-39-38-48-106(103)108)157(252)203-118(72-90(5)6)158(253)212-138(91(7)8)165(260)200-110(52-43-70-182-172(177)178)149(244)184-81-130(225)193-109(51-42-69-181-171(175)176)148(243)187-84-137(236)237)196-144(239)95(13)189-143(238)94(12)191-152(247)114(58-63-127(174)222)194-131(226)82-185-151(246)113(61-66-134(230)231)198-155(250)117(71-89(3)4)202-156(251)119(75-102-54-56-105(221)57-55-102)205-162(257)124(85-216)208-164(259)126(87-218)209-166(261)139(92(9)10)213-161(256)123(78-136(234)235)206-163(258)125(86-217)210-169(264)142(99(17)220)215-160(255)121(74-101-46-35-32-36-47-101)207-168(263)141(98(16)219)211-132(227)83-186-150(245)112(60-65-133(228)229)197-145(240)96(14)190-147(242)107(173)77-104-80-179-88-188-104/h31-36,38-39,44-49,54-57,79-80,88-99,107,109-126,138-142,183,216-221H,18-30,37,40-43,50-53,58-78,81-87,173H2,1-17H3,(H2,174,222)(H,179,188)(H,180,223)(H,184,244)(H,185,246)(H,186,245)(H,187,243)(H,189,238)(H,190,242)(H,191,247)(H,192,262)(H,193,225)(H,194,226)(H,195,224)(H,196,239)(H,197,240)(H,198,250)(H,199,248)(H,200,260)(H,201,241)(H,202,251)(H,203,252)(H,204,249)(H,205,257)(H,206,258)(H,207,263)(H,208,259)(H,209,261)(H,210,264)(H,211,227)(H,212,253)(H,213,256)(H,214,254)(H,215,255)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,265,266)(H4,175,176,181)(H4,177,178,182)/t93-,94-,95-,96-,97-,98+,99+,107-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,138-,139-,140-,141-,142-/m0/s1
InChI Key
YSDQQAXHVYUZIW-QCIJIYAXSA-N

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