γ-2-MSH (41-58), amide is derived from γ-2-MSH. γ-2-MSH is a twelve amino acid peptide that is derived from the N-terminal fragment of proopiomelanocortin (POMC) and contains the His-Phe-Arg-Trp motif common to all melanocortin endogenous agonist ligands.
Registration of APIs CMC information required for an IND
IND and NDA support Drug master files (DMF) filing
M.F/Formula | C₇₄H₁₀₀N₂₂O₁₅S |
M.W/Mr. | 1569.79 |
Sequence | One Letter Code: YVMGHFRWDRFG-NH2 three Letter Code: Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly |
Length | 12 |
2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
4. TMEM16F and dynamins control expansive plasma membrane reservoirs
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