Acetyl Hexapeptide-37

Acetyl Hexapeptide-37 is a synthetic peptide composed of six amino acids, designed for use in cosmetic formulations targeting skin hydration and improved barrier function. This peptide supports the delivery of moisture to the epidermis and assists in maintaining optimal skin homeostasis. Its compatibility with a range of formulation types makes it suitable for inclusion in facial care, serums, and moisturizing products aimed at enhancing skin appearance and texture.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1669

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C22H34N6O8
M.W/Mr.
526.55
Functions
Boosts Aquaporin-3 which promotes inner hydration mechanisms and water movement from the basal layer of epidermis and to the stratum corneum, rejuvenating the skin by improving barrier function, collagen I synthesis and cellular proliferation.

Mechanism of Action (MOA)

Acetyl Hexapeptide-37 is a synthetic signaling peptide that interacts with cellular communication pathways in the epidermis. It is designed to modulate the activity of aquaporin channels, specifically Aquaporin 3 (AQP3), thereby supporting optimized water flux and homeostasis within skin cells. By influencing these protein channels, Acetyl Hexapeptide-37 contributes to the regulation of moisture movement and cellular hydration processes at the biochemical level.

Acetyl Hexapeptide-37 is suitable for incorporation into a variety of cosmetic formulations.

- Facial serums and creams
- Eye contour products
- Moisturizing lotions and emulsions
- Sheet masks and leave-on treatments
- Lightweight gel formulations
- Daily skincare routines targeting the face and neck

INCIName
Acetyl Hexapeptide-37

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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

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