Acetyl Tetrapeptide-15 is a synthetic peptide designed for use in cosmetic formulations targeting sensitive skin. This tetrapeptide is recognized for its ability to help improve skin comfort by supporting the skin's natural response to external aggressors. Suitable for a variety of leave-on applications, Acetyl Tetrapeptide-15 is compatible with global cosmetic regulations and is typically incorporated into products aimed at enhancing skin tolerance and overall appearance.
CAT No: CPC1664
CAS No:928007-64-1
Synonyms/Alias:Acetyl tetrapeptide-15;928007-64-1;Skinasensyl;Ac-tyr-pro-phe-phe-NH2;6K389LE0MV;UNII-6K389LE0MV;(S)-1-((S)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl)-N-((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide;Acetyl tetrapeptide-15 [INCI];L-Phenylalaninamide, N-acetyl-L-tyrosyl-L-prolyl-L-phenylalanyl-;(2S)-1-[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide;(S)-1-(Acetyl-L-tyrosyl)-N-((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide;SCHEMBL3400800;N-Acetyl-L-tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide;Skinasensyl;BSXFOBDOGHFWOC-KRCBVYEFSA-N;HY-P1626;AKOS040744603;AT41624;MS-30723;CS-0064040;Q27265035;895-468-3;
Mechanism of Action (MOA)
Acetyl Tetrapeptide-15 is a biomimetic tetrapeptide designed to interact with the skin's cellular communication pathways. It is known to modulate the activity of the transient receptor potential vanilloid-1 (TRPV1) channel, a key mediator in skin sensitivity. By influencing TRPV1 signaling, Acetyl Tetrapeptide-15 helps support a balanced response to external stimuli, contributing to the maintenance of skin comfort and resilience.
Acetyl Tetrapeptide-15 can be incorporated into a variety of cosmetic formulations designed for skin care routines.
- Suitable for use in facial creams and lotions- Can be added to soothing serums and emulsions- Compatible with after-sun care products- Appropriate for leave-on masks and gels- May be included in formulations for sensitive skin types
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