Acetyl tetrapeptide-3

Acetyl tetrapeptide-3 is a synthetic peptide composed of four amino acids with an acetylated N-terminus, designed for use in cosmetic formulations targeting hair and scalp care. Recognized for its role in supporting the appearance and condition of hair and skin, this ingredient is suitable for inclusion in serums, leave-on treatments, and scalp care products. It is compatible with a range of formulation types and meets global cosmetic regulatory standards.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Acetyl tetrapeptide-3(CAS 827306-88-7)

CAT No: CPC1690

CAS No:827306-88-7

Synonyms/Alias:Acetyl Tetrapeptide-3;827306-88-7;Folixyl;Kollaren 6;Acetyl tetrapeptide-1;Uxi hair growth peptide;Ac-lys-gly-his-lys-NH2;D1HW9N9QBX;UNII-D1HW9N9QBX;Acetyl tetrapeptide-3 [INCI];L-Lysinamide, N2-acetyl-L-lysylglycyl-L-histidyl-;(2S)-2-[[(2S)-2-[[2-[[(2S)-2-acetamido-6-aminohexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanamide;(S)-2-acetamido-6-amino-N-(2-(((S)-1-(((S)-1,6-diamino-1-oxohexan-2-yl)amino)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)amino)-2-oxoethyl)hexanamide;N2-Acetyl-L-lysylglycyl-L-histidyl-L-lysinamide;AcetylTetrapeptide-3;Acetyl tetrapeptide-3?;HY-W129161;AS-84275;DA-50136;CS-0187299;D83845;Q27275970;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C22H39N9O5
M.W/Mr.
509.6
Sequence
One Letter Code:KGHK
Three Letter Code:Ac-Lys-Gly-His-Lys-NH2
Application
Acetyl Tetrapeptide-3 is an innovative biomimetic peptide combined with a red clover extract. It targets the main causes of hair loss, providing fuller and thicker hair.

Mechanism of Action (MOA)

Acetyl tetrapeptide-3 is a biomimetic signaling peptide composed of four amino acids. It is designed to interact with cellular receptors in the extracellular matrix, supporting the activation of key proteins involved in the anchoring of hair and skin structures. By modulating cellular communication pathways, acetyl tetrapeptide-3 may help optimize the environment for extracellular matrix integrity and contribute to the maintenance of normal biological functions in cosmetic applications.

Acetyl tetrapeptide-3 is suitable for incorporation into various cosmetic formulations targeting hair and scalp care.

- Add to leave-in hair serums and tonics
- Incorporate into scalp treatment lotions
- Use in rinse-off or leave-on conditioners
- Include in hair masks and balms
- Formulate in pre-shampoo scalp treatments
- Compatible with water-based systems

Long-term Storage Conditions
Soluble in DMSO
Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C22H39N9O5/c1-14(32)29-17(7-3-5-9-24)21(35)27-12-19(33)30-18(10-15-11-26-13-28-15)22(36)31-16(20(25)34)6-2-4-8-23/h11,13,16-18H,2-10,12,23-24H2,1H3,(H2,25,34)(H,26,28)(H,27,35)(H,29,32)(H,30,33)(H,31,36)/t16-,17-,18-/m0/s1
InChI Key
RRJOMESUBQAYOA-BZSNNMDCSA-N

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