AcFWKYCV contains aromatic and hydrophobic residues flanked by cysteines capable of forming stabilizing disulfide bridges. The acetylated N-terminus modulates charge and folding behavior. Researchers analyze its structural transitions and binding interactions. Applications include peptide engineering, motif analysis, and structural-biophysics research.
CAT No: R2546
CAS No:342878-90-4
Synonyms/Alias:342878-90-4;ACFWKYCV;2-[[10-(4-aminobutyl)-19-(2-aminopropanoylamino)-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid;Urotensin II-Related Peptide (human, mouse, rat) trifluoroacetate salt;PUT-4408-V;DA-58914;FU109712;Urotensin II-Related Peptide (Human, Rat);H-Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH; H-ACFWKYCV-OH;Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val, Urotensin II-Related Peptide;(S)-2-((Z)-(((4R,5Z,7S,8Z,10S,11Z,13S,14Z,16S,17Z,19R)-13-((1H-indol-3-yl)methyl)-19-((Z)-((S)-2-amino-1-hydroxypropylidene)amino)-10-(4-aminobutyl)-16-benzyl-6,9,12,15,18-pentahydroxy-7-(4-hydroxybenzyl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosa-5,;
Acfwkycv is a synthetic carbohydrate compound that has garnered significant attention in the scientific community due to its unique structural attributes and versatile functional properties. Characterized by its distinct sequence and configuration, Acfwkycv offers researchers a reliable tool for probing carbohydrate-related biological processes. Its stability under various experimental conditions and compatibility with a wide range of analytical techniques make it an attractive choice for laboratory investigations. The compound's design enables precise manipulation and integration into complex experimental setups, facilitating the exploration of carbohydrate interactions, recognition mechanisms, and molecular signaling pathways. As a result, Acfwkycv has become an essential component in the toolkit of glycobiology, biochemistry, and molecular biology laboratories seeking to advance the understanding of carbohydrate-mediated phenomena.
Glycobiology Research: Acfwkycv serves as a valuable probe in glycobiology research, where it is employed to elucidate the roles of specific carbohydrate motifs in cellular processes. By incorporating this compound into in vitro and cell-based assays, scientists can investigate how carbohydrate recognition influences cell signaling, adhesion, and immune responses. Its defined structure allows for the dissection of molecular interactions with lectins, glycosyltransferases, and other carbohydrate-binding proteins, providing insights into the dynamic nature of glycan-mediated communication. The use of Acfwkycv in these studies aids in mapping the functional landscape of carbohydrates in health and disease, supporting the development of novel hypotheses and experimental approaches.
Biochemical Pathway Elucidation: In the context of biochemical pathway analysis, Acfwkycv is utilized to trace and characterize enzymatic modifications of carbohydrates. Researchers leverage its synthetic origin and well-defined sequence to monitor the activity of glycosidases, glycosyltransferases, and related enzymes. By tracking the transformation of Acfwkycv within enzymatic cascades, scientists can identify key regulatory steps, substrate specificities, and potential points of intervention. This application is particularly valuable for dissecting the complexities of carbohydrate metabolism and for understanding how alterations in glycan processing contribute to physiological and pathological states.
Analytical Method Development: The unique properties of Acfwkycv make it an ideal standard or reference material in the development and validation of analytical methods for carbohydrate detection and quantification. Its consistent behavior in chromatographic, spectroscopic, and mass spectrometric platforms enables the calibration and benchmarking of analytical workflows. By providing a reproducible and well-characterized analyte, Acfwkycv supports the optimization of sample preparation, separation, and detection protocols. This utility is critical for ensuring the accuracy and reliability of carbohydrate analysis in diverse research and industrial settings.
Molecular Interaction Studies: Researchers frequently employ Acfwkycv to investigate the mechanisms underlying carbohydrate-protein and carbohydrate-ligand interactions. Through binding assays, surface plasmon resonance, and isothermal titration calorimetry, the compound facilitates detailed characterization of binding affinities, kinetics, and thermodynamic parameters. These studies are instrumental in deciphering the structural determinants of recognition and specificity, enabling the rational design of molecules that modulate carbohydrate-mediated interactions. The insights gained from such investigations have broad implications for understanding cell communication, signaling, and molecular recognition events.
Biomaterials and Surface Engineering: In the field of biomaterials science, Acfwkycv is integrated into surface modification protocols to impart carbohydrate functionality to materials and devices. By immobilizing the compound onto substrates, researchers can create glycosylated surfaces that mimic natural cellular environments or enable selective binding of target molecules. This approach is widely employed in the design of biosensors, affinity purification systems, and cell culture platforms, where the presence of specific carbohydrate motifs enhances performance and specificity. The versatility of Acfwkycv in surface engineering underscores its value in advancing biomaterials research and the development of innovative biointerfaces.
Chemical Biology Probes: Acfwkycv is increasingly recognized as a powerful chemical biology probe for dissecting the roles of carbohydrates in complex biological systems. Its synthetic accessibility and modularity allow for the incorporation of reporter groups, affinity tags, or photoactivatable moieties, expanding its utility in labeling, imaging, and crosslinking applications. Researchers exploit these features to visualize carbohydrate dynamics, map interaction networks, and capture transient complexes in situ. The deployment of Acfwkycv as a chemical probe accelerates the discovery of new biological functions and regulatory mechanisms associated with carbohydrates, driving progress at the intersection of chemistry and biology.
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