(Ala22)-Stichodactyla helianthus Neurotoxin (ShK) is a modified sea-anemone peptide featuring an alanine substitution that alters packing within its cystine-stabilized framework. The change modulates channel-binding behavior and structural rigidity. Its characteristics support research on potassium channel modulation and toxin-receptor interfaces. Researchers use it to explore sequence determinants guiding ion-channel specificity.
3. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment
5. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
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