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Alamandine

Alamandine is a heptapeptide belonging to the renin-angiotensin family, exhibiting distinct structural motifs that influence receptor-binding landscapes. Its sequence combines aromatic, charged, and aliphatic residues, supporting studies of helix formation and solvent-driven conformational shifts. Researchers use it to investigate peptide-membrane interactions and molecular recognition mechanisms. Its well-defined architecture aids advanced biophysical analysis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Alamandine(CAS 1176306-10-7)

CAT No: PI-016

CAS No:1176306-10-7

Synonyms/Alias:alamandine;1176306-10-7;Ala-Arg-Val-Tyr-Ile-His-Pro;(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxylic acid;L-Alanyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-proline;GTPL6065;CHEBI:190281;HY-P3108;AKOS040755865;DA-70667;MS-31578;CS-0145495;C20971;G17776;

Chemical Name:(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxylic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C40H62N12O9
M.W/Mr.
855
Sequence
One Letter Code:ARVYIHP
Three Letter Code:H-Ala-Arg-Val-Tyr-Ile-His-Pro-OH
InChI
InChI=1S/C40H62N12O9/c1-6-22(4)32(37(58)49-29(18-25-19-44-20-46-25)38(59)52-16-8-10-30(52)39(60)61)51-35(56)28(17-24-11-13-26(53)14-12-24)48-36(57)31(21(2)3)50-34(55)27(47-33(54)23(5)41)9-7-15-45-40(42)43/h11-14,19-23,27-32,53H,6-10,15-18,41H2,1-5H3,(H,44,46)(H,47,54)(H,48,57)(H,49,58)(H,50,55)(H,51,56)(H,60,61)(H4,42,43,45)/t22-,23-,27-,28-,29-,30-,31-,32-/m0/s1
InChI Key
QVMYBFKDLPBYSO-GIGALADGSA-N
Canonical SMILES
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)N
Isomeric SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)N

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