Antazoline Sulfate
Antistine-Privine (Antazoline Sulfate) is a 1st generation antihistamine, with good anticholinergic properties. It is used to relieve nasal congestion and added in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
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CAT# | 10-101-110 |
CAS | 91-75-8 (net), 24359-81-7 (sulfate) |
Synonyms/Alias | 2-(N-Phenyl-N-benzyl-aminomethyl)imidazoline · sulfate; 2-[(N-Benzylanilino)methyl]-2-imidazoline · sulfate; 4,5-Dihydro-N-phenyl-N-(phenylmethyl)-1H-imidazole-2-methanamine · sulfate |
Chemical Name | N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline;sulfuric acid |
M.F/Formula | C17H19N3·H2O4S |
M.W/Mr. | 363.35 |
Labeling Target | Histamine Receptor |
Application | Conjunctivitis |
Appearance | Solid powder |
Purity | >98% (or refer to the Certificate of Analysis) |
Activity | Antagonist |
Areas of Interest | Neurological Disease |
Target | Histamine H1 receptor |
Source# | Synthetic |
Solubility | Soluble in DMSO |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Short-term Storage Conditions | Dry, dark and at 0 - 4 °C |
Long-term Storage Conditions | -20 °C |
InChI | InChI=1S/C17H19N3/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16/h1-10H,11-14H2,(H,18,19) |
InChI Key | REYFJDPCWQRWAA-UHFFFAOYSA-N |
Canonical SMILES | C1CN=C(N1)CN(CC2=CC=CC=C2)C3=CC=CC=C3.OS(=O)(=O)O |
BoilingPoint | 475.5±38.0 °C at 760 mmHg |
ShelfLife | >2 years if stored properly |
Melting Point | 159ºC |
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