ATN-161 is a novel peptide antagonist of integrin α5β1. ATN-161 selectively binds to and blocks the receptor for integrin α5β1, thereby preventing integrin alpha5beta1 binding. This receptor blockade may result in inhibition of endothelial cell-cell interactions, endothelial cell-matrix interactions, angiogenesis, and tumor progression. It has potential antineoplastic activity.
CAT No: R0965
CAS No:262438-43-7
Synonyms/Alias:ATN-161;262438-43-7;ATN 161;Ac-PHSCN-NH2;ATN-161 free base;UNII-XW0H5LE42K;XW0H5LE42K;DTXSID60180877;L-Aspartamide, 1-acetyl-L-prolyl-L-histidyl-L-seryl-L-cysteinyl-;Acetyl-prolyl-histidyl-seryl-cysteinyl-asparaginamide;(2S)-2-(((2R)-2-(((2S)-2-(((2S)-2-(((2S)-1-ACETYLPYRROLIDINE-2-CARBONYL)AMINO)-3-(1H-IMIDAZOL-4-YL)PROPANOYL)AMINO)-3-HYDROXY-PROPANOYL)AMINO)-3-SULFANYL-PROPANOYL)AMINO)BUTANEDIAMIDE;(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-acetylpyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-sulfanylpropanoyl]amino]butanediamide;(S)-2-((R)-2-((S)-2-((S)-2-((S)-1-Acetylpyrrolidine-2-carboxamido)-3-(1H-imidazol-4-yl)propanamido)-3-hydroxypropanamido)-3-mercaptopropanamido)succinamide;Ac-Pro-His-Ser-Cys-Asn-NH2;SCHEMBL2157375;CHEMBL4297456;SCHEMBL17262996;DTXCID00103368;GLXC-04869;ATN-161?;MKA43843;ATN-161 (Ac-PHSCN-NH2);262438-43-7 (free base);s8454;Alpha V Beta 1 Inhibitor ATN-161;AKOS030210988;AKOS040732486;CCG-270186;CS-3327;BS-16323;DA-71103;HY-13535;D83668;BRD-K00521308-019-01-9;(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-{[(2S)-1-acetylpyrrolidin-2-yl]formamido}-3-(1H-imidazol-4-yl)propanamido]-3-hydroxypropanamido]-3-sulfanylpropanamido]succinamide;(S)-2-((R)-2-((S)-2-((S)-2-((S)-1-acetylpyrrolidine-2-carboxamido)-3-(1H-imidazol-5-yl)propanamido)-3-hydroxypropanamido)-3-mercaptopropanamido)succinamide;
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