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BA 1

BA 1 is a potent agonist for bombesin receptor subtype 3 (BRS-3), also for GRPR (BB1) and NMBR (BB2) (IC50 values are 0.26 and 1.55 nM respectively). It also enhances glucose transport in obese and diabetic primary myocytes.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
BA 1(CAS 183241-31-8)

CAT No: R0806

CAS No:183241-31-8

Synonyms/Alias:183241-31-8;BA 1;BA 1 TFA;BA1;AKOS025293512;AS-86040;DA-71260;PD080061;G79412;H-D-Tyr-Gln-Trp-Ala-Val-Ala-His-Phe-Nle-NH2;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C57H76N14O11
M.W/Mr.
1133.3
Sequence
One Letter Code:YQWAVAHFX
Three Letter Code:H-D-Tyr-Gln-Trp-Ala-Val-Ala-His-Phe-Nle-NH2
Labeling Target
Potent bombesin receptor subtype 3 (BRS-3)
Activity
Agonist
InChI
InChI=1S/C57H76N14O11/c1-6-7-16-42(49(60)74)66-55(80)44(25-34-13-9-8-10-14-34)69-56(81)46(27-37-29-61-30-63-37)68-50(75)32(4)65-57(82)48(31(2)3)71-51(76)33(5)64-54(79)45(26-36-28-62-41-17-12-11-15-39(36)41)70-53(78)43(22-23-47(59)73)67-52(77)40(58)24-35-18-20-38(72)21-19-35/h8-15,17-21,28-33,40,42-46,48,62,72H,6-7,16,22-27,58H2,1-5H3,(H2,59,73)(H2,60,74)(H,61,63)(H,64,79)(H,65,82)(H,66,80)(H,67,77)(H,68,75)(H,69,81)(H,70,78)(H,71,76)/t32-,33-,40+,42-,43-,44-,45-,46-,48-/m0/s1
InChI Key
BXSSCSKCOFKPOK-ZWAOGYCRSA-N
Isomeric SMILES
CCCC[C@@H](C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H](CC5=CC=C(C=C5)O)N

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