BA 1

Name: BA 1
Brand: Creative Peptides
SKU: R0806
Availability: MadeToOrder

BA 1 is a potent agonist for bombesin receptor subtype 3 (BRS-3), also for GRPR (BB1) and NMBR (BB2) (IC50 values are 0.26 and 1.55 nM respectively). It also enhances glucose transport in obese and diabetic primary myocytes.

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CAT No: R0806

CAS No: 183241-31-8

Synonyms/Alias: 183241-31-8;BA 1;BA 1 TFA;BA1;AKOS025293512;AS-86040;DA-71260;PD080061;G79412;H-D-Tyr-Gln-Trp-Ala-Val-Ala-His-Phe-Nle-NH2;

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M.F/Formula	C57H76N14O11
M.W/Mr.	1133.3
Sequence	One Letter Code:YQWAVAHFX Three Letter Code:H-D-Tyr-Gln-Trp-Ala-Val-Ala-His-Phe-Nle-NH2
Labeling Target	Potent bombesin receptor subtype 3 (BRS-3)
Activity	Agonist

InChI	InChI=1S/C57H76N14O11/c1-6-7-16-42(49(60)74)66-55(80)44(25-34-13-9-8-10-14-34)69-56(81)46(27-37-29-61-30-63-37)68-50(75)32(4)65-57(82)48(31(2)3)71-51(76)33(5)64-54(79)45(26-36-28-62-41-17-12-11-15-39(36)41)70-53(78)43(22-23-47(59)73)67-52(77)40(58)24-35-18-20-38(72)21-19-35/h8-15,17-21,28-33,40,42-46,48,62,72H,6-7,16,22-27,58H2,1-5H3,(H2,59,73)(H2,60,74)(H,61,63)(H,64,79)(H,65,82)(H,66,80)(H,67,77)(H,68,75)(H,69,81)(H,70,78)(H,71,76)/t32-,33-,40+,42-,43-,44-,45-,46-,48-/m0/s1
InChI Key	BXSSCSKCOFKPOK-ZWAOGYCRSA-N
Isomeric SMILES	CCCC[C@@H](C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H](CC5=CC=C(C=C5)O)N

1. Cationic cell-penetrating peptides are potent furin inhibitors

2. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy

3. Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency

4. High fat diet and GLP-1 drugs induce pancreatic injury in mice

5. Constitutive and inflammation-dependent antimicrobial peptides produced by epithelium are differentially processed and inactivated by the commensal Finegoldia magna and the pathogen Streptococcus pyogenes

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