BA 1

BA 1 is a potent agonist for bombesin receptor subtype 3 (BRS-3), also for GRPR (BB1) and NMBR (BB2) (IC50 values are 0.26 and 1.55 nM respectively). It also enhances glucose transport in obese and diabetic primary myocytes.

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CAT No: R0806

CAS No: 183241-31-8

Synonyms/Alias: 183241-31-8;BA 1;BA 1 TFA;BA1;AKOS025293512;AS-86040;DA-71260;PD080061;G79412;H-D-Tyr-Gln-Trp-Ala-Val-Ala-His-Phe-Nle-NH2;

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Specification Technical Data Publications Customer reviews and Q&A
M.F/FormulaC57H76N14O11
M.W/Mr.1133.3
SequenceOne Letter Code:YQWAVAHFX
Three Letter Code:H-D-Tyr-Gln-Trp-Ala-Val-Ala-His-Phe-Nle-NH2
Labeling TargetPotent bombesin receptor subtype 3 (BRS-3)
ActivityAgonist
InChIInChI=1S/C57H76N14O11/c1-6-7-16-42(49(60)74)66-55(80)44(25-34-13-9-8-10-14-34)69-56(81)46(27-37-29-61-30-63-37)68-50(75)32(4)65-57(82)48(31(2)3)71-51(76)33(5)64-54(79)45(26-36-28-62-41-17-12-11-15-39(36)41)70-53(78)43(22-23-47(59)73)67-52(77)40(58)24-35-18-20-38(72)21-19-35/h8-15,17-21,28-33,40,42-46,48,62,72H,6-7,16,22-27,58H2,1-5H3,(H2,59,73)(H2,60,74)(H,61,63)(H,64,79)(H,65,82)(H,66,80)(H,67,77)(H,68,75)(H,69,81)(H,70,78)(H,71,76)/t32-,33-,40+,42-,43-,44-,45-,46-,48-/m0/s1
InChI KeyBXSSCSKCOFKPOK-ZWAOGYCRSA-N
Isomeric SMILESCCCC[C@@H](C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H](CC5=CC=C(C=C5)O)N

1. The effect of B-type allatostatin neuropeptides on crosstalk between the insect immune response and cold tolerance

2. Effect of Probiotic Lactobacillus plantarum on Streptococcus mutans and Candida albicans Clinical Isolates from Children with Early Childhood Caries

3. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists

4. Effect of Short-Term Desiccation, Recovery Time, and CAPA-PVK Neuropeptide on the Immune System of the Burying Beetle Nicrophorus vespilloides

5. Glucagonlike peptide 2 analogue teduglutide: stimulation of proliferation but reduction of differentiation in human Caco-2 intestinal epithelial cells

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    Carbetocin is a long-acting synthetic agonist analogue of human oxytocin, with antihemorrhagic and uterotonic activities. Upon administration, carbetocin targets, binds to and activates peripheral oxytocin receptors that are present on the smooth musculature of the uterus. This causes uterus contractions and prevents excessive bleeding after childbirth, particularly following Cesarean section, and may be used to decrease blood loss during hysteroscopic myomectomy.

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