β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity.
Registration of APIs CMC information required for an IND
IND and NDA support Drug master files (DMF) filing
Synonyms/Alias | 149385-65-9;H-ILE-ILE-GLY-LEU-MET-OH;AMYLOID Beta-PROTEIN (31-35);(2S)-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid;beta-Amyloid (31-35);MFCD06659094;-Amyloid (31-35);??Amyloid (31-35);Isoleucinyl-isoleucinyl-glycinyl-leucinyl-methionine;CHEMBL272776;HY-P1517;DA-70829;FA109633;MS-30013;CS-0044618;G13359;Amyloid b-Protein (31-35) (H-Ile-Ile-Gly-Leu-Met-OH); |
M.F/Formula | C25H47N5O6S |
M.W/Mr. | 545.7 |
Sequence | One Letter Code:IIGLM Three Letter Code:H-Ile-Ile-Gly-Leu-Met-OH |
InChI | InChI=1S/C25H47N5O6S/c1-8-15(5)20(26)23(33)30-21(16(6)9-2)24(34)27-13-19(31)28-18(12-14(3)4)22(32)29-17(25(35)36)10-11-37-7/h14-18,20-21H,8-13,26H2,1-7H3,(H,27,34)(H,28,31)(H,29,32)(H,30,33)(H,35,36)/t15-,16-,17-,18-,20-,21-/m0/s1 |
InChI Key | ZMDGLWRNBGRYQB-ZKHIMWLXSA-N |
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