Big Gastrin-1, human represents a larger progastrin-derived peptide containing acidic residues that coordinate metal ions and influence structural folding. The extended sequence is used to explore biosynthetic processing, receptor-contact motifs, and conformational transitions. Researchers employ it in studies of peptide maturation and enzymatic cleavage. Its complexity supports detailed structural mapping.
1. High fat diet and GLP-1 drugs induce pancreatic injury in mice
5. TMEM16F and dynamins control expansive plasma membrane reservoirs
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