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BIM-23190

BIM-23190 is a synthetic peptide analog used to probe receptor-specific binding and conformational changes within targeted signaling pathways. The sequence contains hydrophobic and charged residues influencing secondary structure. Researchers employ it to dissect ligand architecture and binding kinetics. Its stability supports extensive biophysical evaluation.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
BIM-23190(CAS 182153-96-4)

CAT No: PI-008

CAS No:182153-96-4

Synonyms/Alias:BIM-23190;182153-96-4;BIM 23190;V55PUY46VR;(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-7-ethyl-19-[[(2R)-2-[[2-[4-(2-hydroxyethyl)piperazin-1-yl]acetyl]amino]-3-phenylpropanoyl]amino]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide;L-THREONINAMIDE, N-(2-(4-(2-HYDROXYETHYL)-1-PIPERAZINYL)ACETYL)-D-PHENYLALANYL-L-CYSTEINYL-L-TYROSYL-D-TRYPTOPHYL-L-LYSYL-(2S)-2-AMINOBUTANOYL-L-CYSTEINYL-, CYCLIC (2->7)-DISULFIDE;BDBM85051;HY-P3124;CS-0146506;L-Threoninamide, N-((4-(2-hydroxyethyl)-1-piperazinyl)acetyl)-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-(2S)-2-aminobutanoyl-L-cysteinyl-, cyclic (2-7)-disulfide;L-Threoninamide, N-((4-(2-hydroxyethyl)-1-piperazinyl)acetyl)-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-2-aminobutanoyl-L-cysteinyl-, cyclic (2-7)-disulfide;L-Threoninamide, N-[2-[4-(2-hydroxyethyl)-1-piperazinyl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-(2S)-2-aminobutanoyl-L-cysteinyl-, cyclic (2-->7)-disulfide;N-(N'-(2-hydroxyethyl)-piperazinyl)-2-acetyl-Phe-Cys-Tyr-Trp-Lys-Abu-Cys-Thr-NH2 disulfide;N-(N'-(2-hydroxyethyl)piperazinyl)-2-acetyl-phenylalanyl-cysteinyl-tyrosyl-tryptophyl-lysyl-2-aminobutanoyl-cysteinyl-threoninamide disulfide;

Chemical Name:(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-7-ethyl-19-[[(2R)-2-[[2-[4-(2-hydroxyethyl)piperazin-1-yl]acetyl]amino]-3-phenylpropanoyl]amino]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C57H79N13O12S2
M.W/Mr.
1202.5
InChI
InChI=1S/C57H79N13O12S2/c1-3-40-51(76)66-47(57(82)68-49(34(2)72)50(59)75)33-84-83-32-46(67-53(78)43(27-35-11-5-4-6-12-35)61-48(74)31-70-23-21-69(22-24-70)25-26-71)56(81)64-44(28-36-16-18-38(73)19-17-36)54(79)65-45(29-37-30-60-41-14-8-7-13-39(37)41)55(80)63-42(52(77)62-40)15-9-10-20-58/h4-8,11-14,16-19,30,34,40,42-47,49,60,71-73H,3,9-10,15,20-29,31-33,58H2,1-2H3,(H2,59,75)(H,61,74)(H,62,77)(H,63,80)(H,64,81)(H,65,79)(H,66,76)(H,67,78)(H,68,82)/t34-,40+,42+,43-,44+,45-,46+,47+,49+/m1/s1
InChI Key
YIGPOHXLINPVGT-CVGVOFIUSA-N
Canonical SMILES
CCC1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)CN6CCN(CC6)CCO)C(=O)NC(C(C)O)C(=O)N
Isomeric SMILES
CC[C@H]1C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)[C@@H](CC5=CC=CC=C5)NC(=O)CN6CCN(CC6)CCO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N

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