Caspase1 Inhibitor II is also known as IL-1β Converting Enzyme (ICE) Inhibitor; Biotin-YVAD-CMK rescues neuronal cells from cell death in response to oxidative stress and oxygen/glucose deprivation.
Registration of APIs CMC information required for an IND
IND and NDA support Drug master files (DMF) filing
M.W/Mr. | 725.3 |
Sequence | One Letter Code: Biotin-YVAD-CMK Three Letter Code: Biotin-Tyr-Val-Ala-Asp-Chloromethyl Ketone |
References | 1. Ref: Murphy, B. et al. J. Biol. Chem. 279, 36916 (2004); 2. Fahy, R. et al. J. Immunol. 163, 1755 (1999). |
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