Biotinoyl-Tripeptide-1 trifluoroacetate is a labeled tripeptide incorporating a biotin moiety to facilitate affinity-based interactions. The peptide backbone supports studies of ligand anchoring, folding, and protein-binding specificity. Researchers apply it in structural profiling and conjugation strategies. The TFA salt improves solubility for analytical applications.
CAT No: R2206
CAS No:2828433-27-6
Synonyms/Alias:Biotinoyl-Tripeptide-1 trifluoroacetate;2828433-27-6;G70431;
Biotinoyl-Tripeptide-1 trifluoroacetate is a specialized peptide-carbohydrate conjugate that combines the hair-strengthening benefits of biotin with the signaling capabilities of a synthetic tripeptide, all stabilized as a trifluoroacetate salt. This innovative compound is widely recognized for its multifunctional properties in cosmetic science, particularly within the domains of hair care, skin rejuvenation, and advanced cosmetic formulations. Its unique structure enables it to interact with biological systems at the cellular level, promoting targeted activity that supports the appearance and vitality of hair and skin. As a hybrid molecule, Biotinoyl-Tripeptide-1 trifluoroacetate offers enhanced solubility and stability, making it a valuable ingredient for research and formulation development in personal care and cosmetic industries.
Hair Growth Research: As a key active ingredient in hair follicle biology studies, Biotinoyl-Tripeptide-1 trifluoroacetate is frequently utilized to investigate mechanisms involved in hair growth and hair anchoring. Researchers employ it in in vitro and ex vivo models to examine its effects on the expression of key extracellular matrix proteins and adhesion molecules within the dermal papilla. The peptide's biotin moiety is known to support cellular metabolism, while the tripeptide fragment can activate signaling pathways associated with hair shaft anchorage and follicle vitality. These attributes make it a preferred tool for exploring strategies to minimize hair loss and improve hair density through non-pharmaceutical means.
Cosmetic Formulation Development: In the field of cosmetic chemistry, Biotinoyl-Tripeptide-1 trifluoroacetate is employed as a functional ingredient to develop advanced hair and eyebrow care products. Its dual-action mechanism—providing both nutritional support from biotin and peptide-based stimulation—enables formulators to design products that target the appearance of thinning hair and promote a fuller, healthier look. By incorporating this compound into serums, conditioners, or leave-in treatments, cosmetic scientists can enhance the efficacy of their formulations, allowing for improved penetration and activity at the scalp or brow area.
Skin Rejuvenation Studies: Beyond its applications in hair care, Biotinoyl-Tripeptide-1 trifluoroacetate is also explored for its potential role in skin revitalization. Researchers investigate its impact on the synthesis of collagen and other matrix proteins within the dermis, aiming to elucidate its ability to support the maintenance of skin elasticity and firmness. The peptide's structure allows it to interact with skin cells and modulate pathways involved in extracellular matrix production, making it a promising candidate for studies focused on reducing the visible signs of aging and enhancing skin texture.
Peptide Delivery System Research: The trifluoroacetate salt form of this compound provides improved stability and solubility compared to other peptide forms, which is advantageous in the development of novel delivery systems. Scientists leverage these properties to design encapsulation or carrier systems that optimize the bioavailability and sustained release of the active molecule. This research direction is particularly relevant for enhancing the performance of cosmeceutical products, ensuring that the active peptide reaches its intended target with maximum efficacy.
Biochemical Mechanism Elucidation: Biotinoyl-Tripeptide-1 trifluoroacetate is also valuable in fundamental biochemical studies aimed at deciphering the molecular mechanisms underlying peptide-biological system interactions. Its defined structure enables precise probing of receptor binding, signal transduction, and the modulation of gene expression in relevant cell types. Such research contributes to a deeper understanding of how synthetic peptides can be engineered for specific biological outcomes, paving the way for the design of next-generation cosmetic actives and biomimetic compounds. Through these diverse applications, Biotinoyl-Tripeptide-1 trifluoroacetate continues to drive innovation and scientific discovery in cosmetic and biochemical research fields.
1. Immune-awakening Saccharomyces-inspired nanocarrier for oral target delivery to lymph and tumors
2. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
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