BM213 is a peptide-like research scaffold containing tailored hydrophobic, aromatic, and polar residues that form defined recognition surfaces. Sequence composition promotes stable secondary structure under physiological conditions. Researchers use it to interrogate protein-ligand contacts and binding thermodynamics. Applications include ligand-discovery screening, structural biophysics, and SAR evaluation.
CAT No: R2756
Synonyms/Alias:BM213; CHEMBL5071478; 2891606-02-1; BDBM50587341; MS-31708; HY-145237; CS-0370230; F83816
BM213 is a specialized carbohydrate compound recognized for its unique molecular structure and versatile chemical properties, making it a valuable tool in various scientific research and industrial applications. Its well-defined configuration allows for selective interactions with biological molecules, which has led to its adoption in diverse fields ranging from glycobiology to materials science. The compound's stability and solubility in aqueous environments further enhance its utility, enabling researchers to incorporate it into a wide array of experimental protocols. With its ability to participate in specific binding events and structural modifications, BM213 stands out as an essential resource for those investigating carbohydrate-mediated processes and developing novel biomolecular tools.
Glycobiology Research: In the realm of glycobiology, BM213 is frequently employed to study carbohydrate-protein interactions, which are fundamental to numerous biological processes such as cell signaling, immune responses, and pathogen recognition. Researchers utilize the compound to probe the specificity of lectins and other carbohydrate-binding proteins, facilitating the mapping of glycan recognition patterns and elucidating the functional roles of complex carbohydrates in biological systems. By serving as a model substrate or ligand in binding assays, BM213 enables the dissection of molecular mechanisms underlying glycan-mediated events, contributing to a deeper understanding of cellular communication and molecular recognition.
Enzyme Substrate Analysis: As a defined carbohydrate, BM213 is invaluable for enzyme substrate analysis, particularly in studies involving glycosidases and glycosyltransferases. Scientists employ it to determine enzyme specificity, catalytic efficiency, and reaction mechanisms, often using it as a standard substrate in kinetic assays. The compound's structural features allow for the assessment of enzyme-substrate affinity and the identification of critical residues involved in catalysis. Such investigations are essential for characterizing enzyme function, engineering novel biocatalysts, and optimizing enzymatic processes for synthetic and analytical applications.
Drug Discovery and Development: Within drug discovery, BM213 is utilized as a molecular probe to investigate carbohydrate-targeting agents, including small molecules and biologics. Its defined structure makes it an ideal candidate for high-throughput screening platforms aimed at identifying inhibitors or modulators of glycan-mediated interactions. By incorporating the compound into binding and inhibition assays, researchers can evaluate the efficacy and selectivity of candidate compounds, accelerating the identification of promising therapeutic leads. Additionally, it provides a reliable reference for structure-activity relationship studies, informing the rational design of carbohydrate-based drug candidates.
Analytical Chemistry and Detection: In analytical chemistry, BM213 serves as a standard or reference compound for the calibration and validation of carbohydrate detection methods. Techniques such as high-performance liquid chromatography (HPLC), mass spectrometry, and capillary electrophoresis rely on well-characterized standards to ensure accuracy and reproducibility in glycan analysis. The compound's stability and defined composition make it suitable for developing and validating quantitative assays, supporting the detection and quantification of carbohydrates in complex biological or synthetic samples. Its use in method development enhances the reliability of analytical workflows across research and quality control laboratories.
Materials Science and Nanotechnology: In the field of materials science, BM213 is explored as a functional building block for the synthesis of carbohydrate-based materials, including hydrogels, nanoparticles, and surface coatings. Its ability to engage in specific molecular interactions enables the design of bioactive surfaces and smart materials with tailored properties. Researchers leverage the compound to create biocompatible interfaces, enhance material functionality, and facilitate targeted delivery systems. The integration of BM213 into advanced materials contributes to innovations in biosensing, drug delivery, and tissue engineering, highlighting its versatility beyond traditional biochemical applications.
Chemical Biology Tool Development: As a tool in chemical biology, BM213 supports the creation of novel probes and affinity reagents for studying carbohydrate-mediated phenomena. Scientists employ it to design labeled derivatives for imaging or pull-down experiments, enabling the visualization and isolation of glycan-binding proteins in complex biological mixtures. Its application in the synthesis of multivalent ligands and conjugates expands the toolkit available for dissecting carbohydrate function and dynamics in living systems. Through these diverse roles, BM213 continues to drive progress in both fundamental research and applied science, underscoring its significance as a multifaceted carbohydrate compound.
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