Cemadotin

Cemadotin, an omnipotent cytotoxic entity, is extensively employed in the mesmerizing biomedical realm to efficaciously combat an array of obstinate solid tumors encompassing pulmonary, mammary, as well as ovarian malignancies. Its extraordinary prowess lies within its exquisite ability to unequivocally pinpoint and curtail the polymerization of tubulin, thus imposing a profound halt upon the cell cycle, ultimately inducing apoptosis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Cemadotin(CAS 159776-69-9)

CAT No: R2050

CAS No:159776-69-9

Synonyms/Alias:Cemadotin;159776-69-9;Cemadotin [INN];cemadotina;cemadotine;UNII-6SQ8M7ZSFV;6SQ8M7ZSFV;LU 103793;NSC D-669356;NSC-D-669356;CEMADOTIN [WHO-DD];LU-103793;LU103793;N,N-dimethyl-L-valyl-L-valyl-N-methyl-L-valyl-L-prolyl-L-prolinebenzylamide;L-Prolinamide, N,N-dimethyl-L-valyl-L-valyl-N-methyl-L-valyl-L-prolyl-N-(phenylmethyl)-;NSCD-669356;cemadotinum;cemadotin free base;SCHEMBL18768;CHEMBL2104387;DTXCID6089214;NSC 669356D;NSC D669356;NSC-669356D;NSC-D669356;DA-72074;HY-13589;TS-09580;CS-0007296;Q27265457;N,N-Dimethyl-L-valyl-L-valyl-N-methyl-L-valyl-L-prolyl-N-benzyl-L-prolinamide;

Chemical Name:(2S)-N-benzyl-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxamide

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C35H56N6O5
M.W/Mr.
640.9
Sequence
One Letter Code:VVVPP
Three Letter Code:N(Me2)Val-Val-N(Me)Val-Pro-Pro-NHBn
InChI
InChI=1S/C35H56N6O5/c1-22(2)28(37-32(43)29(23(3)4)38(7)8)34(45)39(9)30(24(5)6)35(46)41-20-14-18-27(41)33(44)40-19-13-17-26(40)31(42)36-21-25-15-11-10-12-16-25/h10-12,15-16,22-24,26-30H,13-14,17-21H2,1-9H3,(H,36,42)(H,37,43)/t26-,27-,28-,29-,30-/m0/s1
InChI Key
XSAKVDNHFRWJKS-IIZANFQQSA-N
Canonical SMILES
CC(C)C(C(=O)N(C)C(C(C)C)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC3=CC=CC=C3)NC(=O)C(C(C)C)N(C)C
Isomeric SMILES
CC(C)[C@@H](C(=O)N(C)[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)NCC3=CC=CC=C3)NC(=O)[C@H](C(C)C)N(C)C

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