Collection EBV

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ApplicationT-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response, Patient stratification, Qualification of immune responses
Purity>70% (HPLC-MS)
Areas of InterestInfection, Cancer, Hodgkin's lymphoma, Burkitt's lymphoma, Nasopharyngeal carcinoma, Dermatomyositis, Systemic lupus erythematosus, Rheumatoid arthritis, Sj?gren's syndrome, Multiple sclerosis
Size2 aliquots of 13 peptide pools containing 1μg per peptide /tube
FormatFreeze dried in micro tube rack with individual vials.
NumberOfPeptides2043
OrganismEpstein-Barr virus (HHV-4)
SpecificationsPeptide scan (15mers with 11 aa overlap)
Protein NameSelected proteins
References1."PepMixTM Peptide Pools for Clinical Applications: T cell therapy for viral infections after hematopoietic stem cell transplant"
Leen et al, Application Note (2012)
2."T-cell Therapy for EBV-Associated Nasopharyngeal Carcinoma: Preparative Lymphodepleting Chemotherapy Does not Improve Clinical Results". Secondino et al., Ann. Onc. (2012)
3.Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals Tomaras et al., Journal of Virology (2011)
4."Effective and Long-term Control of EBV PTLD After Transfer of Peptide-Selected T Cells". Moosmann et al., BLOOD (2010)
5."Adoptive Transfer of EBV-specific T Cells Results in Sustained Clinical Responses in Patients With Locoregional Nasopharyngeal Carcinoma". Louis et al., J Immunother (2010)
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