Copper Peptide(GHK-Cu)

Copper Peptide (GHK-Cu) is a biomimetic tripeptide complexed with copper ions, recognized for its role in cosmetic formulations targeting skin revitalization and improved appearance. It supports the maintenance of skin's natural functions by aiding in the visible improvement of skin texture and elasticity. Suitable for use in anti-aging, firming, and conditioning products, GHK-Cu is compatible with a range of topical applications in both leave-on and rinse-off formulations.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Copper Peptide(GHK-Cu)(CAS 89030-95-5)

CAT No: CPC1613

CAS No:89030-95-5

Synonyms/Alias:Prezatide copper;GHK copper;89030-95-5;CG-copper peptide;Copper tripeptide-1;Oristar Cu-GHK;UNII-6BJQ43T1I9;Copper tripeptide;6BJQ43T1I9;copper;(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoate;DTXSID20237492;Copper, (N2-(N-glycyl-L-histidyl)-L-lysinato(2-))-;Copper, (glycyl-kappaN-L-histidyl-kappaN,kappaN3-L-lysinato(2-))-;GHK-Cu;[N2-(N-Glycyl-L-histidyl)-L-lysinato(2-)]copper;Copper tripeptide-1 [INCI];Mask Pack;Copper tripeptide?;Copper Tripeptide 1;Copper tripeptide-1.xHOAc;Skin Delight Mask Pack Plus;DTXCID20159983;Copper peptide(GHK-Cu) TFA salt;Copper Tripeptide-1 (0.001%);Dermaheal Skin Delight Mask Pack Plus;DB14683;FC138108;FC180071;Glycyl-histidyl-lysine monocopper TFA salt;Copper Peptide pound 1:1 pound(c) Acetate;NEWSTEM Rx FRACTIONAL REPAIR Energy Ampoule;A936552;Q27264447;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C14H23CuN6O4+
M.W/Mr.
402.92
Sequence
Gly-His-Lys•Cu•xHOAc
Functions
Copper peptide can tighten the loose skin and improve the skin elasticity, clarity and firmness. It reduces fine lines and deep wrinkles, and is widely used in reparative and anti-aging cosmetics.

Mechanism of Action (MOA)

Copper Peptide (GHK-Cu) is a naturally occurring tripeptide complexed with copper ions. It interacts with cellular pathways by facilitating copper uptake, which is essential for enzymatic activities involved in extracellular matrix maintenance. GHK-Cu modulates the expression of key proteins through signaling cascades, supporting processes such as collagen synthesis and antioxidant defense. This peptide type is recognized for its role in optimizing cellular communication and maintaining a balanced skin microenvironment.

Copper Peptide (GHK-Cu) can be incorporated into a variety of cosmetic formulations for targeted skin and hair care applications:

- Suitable for inclusion in facial serums and creams
- Can be added to eye contour products
- Compatible with lightweight lotions and gels
- Appropriate for overnight masks and leave-on treatments
- May be formulated into scalp and hair care products
- Usable in post-procedure soothing cosmetics

INCIName
Copper tripeptide-1
InChI
InChI=1S/C14H24N6O4.Cu/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);/q;+2/p-1/t10-,11-;/m0./s1
InChI Key
NZWIFMYRRCMYMN-ACMTZBLWSA-M
References
Devita Rx

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