CSP-2, Competence-stimulating peptide -2

CSP-2, Competence-Stimulating Peptide-2 peptide with sequence of EMRISRIILDFLFLRKK are genetic transformation in streptococcus pneumoniae, Streptococcus mitis and Streptococcus oralis is regulated by secreted peptide pheromones named the competence-stimulating peptide (CSP). Different strains and species of these bacteria produce CSP with different primary sequence. Other CSP sequence are: CSP-1 (EMRLSKFFRDFILQRKK), CSP-153 (DKRLPYFFKHLFSNRTK), CSP-612

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: B01038

Custom Peptide Synthesis

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

2178.7

Sequence

Three-Letter Code: H-Glu-Met-Arg-Ile-Ser-Arg-Ile-Ile-Leu-Asp-Phe-Leu-Phe-Leu-Arg-Lys-Lys-OH
One-Letter Code: EMRISRIILDFLFLRKK

References

Francis, K. et al. Infection Immunity 69, 3350 (2001); Johnsborg, O. et al. Mol. Microbio. 69, 245 (2008).

1. Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore

2. TMEM16F and dynamins control expansive plasma membrane reservoirs

3. Effect of Probiotic Lactobacillus plantarum on Streptococcus mutans and Candida albicans Clinical Isolates from Children with Early Childhood Caries

4. Exosomes-mediated Transfer of miR-125a/b in Cell-to-cell Communication: A Novel Mechanism of Genetic Exchange in the Intestinal Microenvironment

5. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy

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