Cyclo(-Leu-Pro)
Cyclo(-Leu-Pro) is a cyclic dipeptide containing leucine and proline. Cyclo(L-Leu-L-Pro) is a homodetic cyclic peptide composed from leucyl and prolyl residues. It has a role as a marine metabolite and a bacterial metabolite. It is a dipeptide, a homodetic cyclic peptide and a pyrrolopyrazine.
Online Inquiry
| CAT# | R1915 |
| Chemical Structure |  |
| CAS | 2873-36-1 |
| Synonyms/Alias | cyclo(Leu-Pro); Cyclo(L-leucyl-L-prolyl) |
| Chemical Name | (3S,8aS)-3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione |
| M.F/Formula | C11H18N2O2 |
| M.W/Mr. | 210.3 |
| Application | Antimicrobial & Antiviral Peptides; Obesity Research |
| Activity | Antimicrobial cyclopeptide |
| Biological Activity | Cyclo(Leu-Pro) showed antibacterial activity. Yan et al. observed that Cyclo(Leu-Pro) produced by Achromobacter xylosoxidans inhibited aflatoxin production by Aspergillus parasiticus. The diketopiperazine was shown to inhibit catecholamine release in vitro. It could play a role in the hypothalamic modulation of appetite suppressant circuitry. |
| Storage | Store at -20°C |
Solubility | Soluble in DMSO |
Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
InChI | InChI=1S/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)/t8-,9-/m0/s1 |
InChI Key | SZJNCZMRZAUNQT-IUCAKERBSA-N |
Canonical SMILES | CC(C)CC1C(=O)N2CCCC2C(=O)N1 |
Isomeric SMILES | CC(C)C[C@H]1C(=O)N2CCC[C@H]2C(=O)N1 |
Write a review
Ask a question
My Review for Cyclo(-Leu-Pro)
Required fields are marked with *
×
Ask a Question for Cyclo(-Leu-Pro)
Required fields are marked with *
×
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
