D-Pro9-Cetrorelix incorporates a D-proline substitution that introduces pronounced conformational restriction at position 9. The change influences backbone curvature, proteolytic resistance, and receptor-contact geometry. Researchers examine its altered binding patterns relative to native cetrorelix. Applications include SAR exploration, peptide stabilization strategies, and structural-biology research.
CAT No: Z10-101-210
Synonyms/Alias:(R)-1-(((R)-2-((S)-2-((S)-2-((R)-2-((R)-2-((R)-2-acetamido-3-(naphthalen-2-yl)propanamido)-3-(4-chlorophenyl)propanamido)-3-(pyridin-3-yl)propanamido)-3-hydroxypropanamido)-3-(4-hydroxyphenyl)propanamido)-5-ureidopentanoyl)-L-leucyl-L-arginyl)-N-((R)-1-amino-1-oxopropan-2-yl)pyrrolidine-2-carboxamide; Ac-D-2-Nal-D-Phe (4-Cl)-D-3-Pal-Ser-Tyr-D-Cit-Leu-Arg-D-Pro-D-Ala-NH2;(R)-N-((R)-1-amino-1-oxopropan-2-yl)-1-((2S,5R,8S,11S,14R,17R,20R)-3-((S)-2-amino-4-methylpentanoyl)-17-(4-chlorobenzyl)-2-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-(hydroxymethyl)-20-(naphthalen-2-ylmethyl)-4,7,10,13,16,19,22-heptaoxo-14-(pyridin-3-ylmethyl)-5-(3-ureidopropyl)-3,6,9,12,15,18,21-heptaazatricosan-1-oyl)pyrrolidine-2-carboxamide
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