Dalda is a peptide analog containing aromatic, hydrophobic, and charged residues that confer well-defined folding patterns. Researchers use it to examine intramolecular interactions, residue-driven geometry, and solvent-dependent conformational change. The sequence supports mapping of ligand-binding determinants. Its stability aids in-depth biophysical evaluation.
CAT No: R2329
CAS No:118476-85-0
Synonyms/Alias:DALDA;118476-85-0;tyrosyl-arginyl-phenylalanyl-lysinamide;CHEMBL60444;(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]hexanamide;Tyr-arg-phe-lys-NH2;CAS_122222;NSC_122222;(D-Arg2,Lys4)-Dermorphin (1-4) amide;UNII-FS8087FL3X;L-Lysinamide, L-tyrosyl-D-arginyl-L-phenylalanyl-;FS8087FL3X;SCHEMBL8975803;BDBM85737;UEVAHGMTRWGMTB-JBXUNAHCSA-N;DTXSID001045851;HY-P3870;EINECS 270-350-9;BDBM50016867;FA110358;CS-0626328;NS00013747;H-Tyr-D-Arg-Phe-Lys-NH2; H-Y(dR)FK-NH2;(S)-6-Amino-2-((S)-2-{(R)-2-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoylamino}-3-phenyl-propionylamino)-hexanoic acid amide;6-amino-2-[1-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-4-amino(imino)methylamino-(1R)-butylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-(2S)-hexanamide;
Dalda is a synthetic triglyceride, primarily composed of hydrogenated vegetable oils, and is widely recognized as a laboratory-grade lipid standard. As a chemically defined fat, it serves as a benchmark compound in biochemical research, particularly in studies involving lipid metabolism, fatty acid analysis, and the functional properties of triglycerides. Its consistent composition and physicochemical stability make it a valuable tool for elucidating the roles of dietary fats in biological systems, supporting a range of experimental protocols that require precise lipid controls. Dalda's relevance extends to metabolic research, analytical chemistry, and technical applications where a uniform triglyceride profile is essential for reproducibility and data integrity.
Lipid metabolism research: Dalda is frequently utilized in the study of lipid metabolic pathways, enabling researchers to investigate the enzymatic breakdown, absorption, and assimilation of triglycerides in biological samples. Its defined structure allows for controlled experimentation on the hydrolysis of fats by lipases, facilitating the exploration of mechanisms underlying lipid digestion and transport. By providing a reproducible substrate, it aids in quantifying enzymatic activity and assessing the effects of various modulators on lipid metabolism.
Analytical standardization: As a reference compound in chromatographic and spectrometric analyses, this synthetic triglyceride supports the accurate quantification and identification of lipid species in complex mixtures. Its uniformity makes it an ideal calibration standard for techniques such as gas chromatography (GC) and high-performance liquid chromatography (HPLC), where precise retention times and response factors are critical for reliable lipid profiling. Utilization of Dalda in analytical workflows enhances the comparability of results across laboratories and experimental runs.
Food science and lipid formulation: In the context of food chemistry, Dalda serves as a model fat for investigating the physical and functional properties of triglycerides in processed foods. Researchers employ it to study melting behavior, crystallization patterns, and emulsion stability, providing insights into the textural and sensory attributes of lipid-containing products. Its application in formulation studies assists in optimizing fat blends and improving the quality and shelf life of food products.
Cell culture and model systems: Dalda is incorporated into cell culture media and model organisms to simulate dietary fat exposure and study lipid uptake, storage, and mobilization at the cellular level. Its defined triglyceride composition allows for controlled manipulation of lipid environments, supporting research into lipid-induced signaling pathways, membrane dynamics, and metabolic adaptations. This approach is particularly valuable for dissecting the cellular responses to specific fat types under experimental conditions.
Biophysical and structural studies: The compound's consistent molecular structure makes it suitable for biophysical investigations into the organization and dynamics of lipid assemblies, such as micelles, vesicles, and bilayers. Researchers leverage Dalda to probe the interactions of triglycerides with proteins, surfactants, and other biomolecules, advancing the understanding of lipid-protein complexes and membrane-associated processes. These studies contribute to the broader knowledge of lipid behavior in both biological and synthetic systems, informing the design of functional materials and delivery vehicles.
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