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Dermorphin, 4-hyp(6)-

Dermorphin, 4-Hyp(6)- is a dermorphin analogue containing 4-hydroxyproline at position 6, altering backbone rigidity and hydrogen-bonding characteristics. The modification influences β-turn formation and aromatic-hydrophobic packing. Researchers examine its structural distribution and receptor-binding determinants. Applications include opioid-peptide motif studies, structural refinement, and analog development.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Dermorphin, 4-hyp(6)-(CAS 77614-17-6)

CAT No: R2386

CAS No:77614-17-6

Synonyms/Alias:Dermorphin, 4-hyp(6)-;6-(4-Hyp)-dermorphin;77614-17-6;Dermorphin, 4-hydroxyproline(6)-;Dermorphin, 6-(trans-4-hydroxy-L-proline)-;DTXSID00228282;H-Tyr-D-Ala-Phe-Gly-Tyr-Hyp-Ser-NH2;DTXCID20150773;Tyr-D-Ala-Phe-Gly-Tyr-Hyp-Ser-NH2;

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  • CMC information required for an IND
  • IND and NDA support
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M.F/Formula
C40H50N8O11
M.W/Mr.
818.9
Sequence
One Letter Code:YAFGYXS
Three Letter Code:H-Tyr-D-Ala-Phe-Gly-Tyr-Hyp-Ser-NH2
InChI
InChI=1S/C40H50N8O11/c1-22(44-37(56)29(41)15-24-7-11-26(50)12-8-24)36(55)46-30(16-23-5-3-2-4-6-23)38(57)43-19-34(53)45-31(17-25-9-13-27(51)14-10-25)40(59)48-20-28(52)18-33(48)39(58)47-32(21-49)35(42)54/h2-14,22,28-33,49-52H,15-21,41H2,1H3,(H2,42,54)(H,43,57)(H,44,56)(H,45,53)(H,46,55)(H,47,58)/t22-,28-,29+,30+,31+,32+,33+/m1/s1
InChI Key
OBMDBUWMBOPDST-JJDRJQAMSA-N

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