Distamycin A is an oligopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces distallicus. Distamycin preferentially binds to adenine-thymine (A-T) rich sequences in the minor groove of DNA, thereby inhibiting DNA replication and RNA transcription. In addition to antitumor effects, distamycin also possesses antiviral and antiprotozoal activities and is used as a chromosome dye.
CAT No: MFP-024
CAS No:39389-47-4
Synonyms/Alias:Stallimycin; Distamycin; Herperetin; Dst-a; Nsc82150; Unii-80o63p88is
Chemical Name:N-[5-[(3-Amino-3-iminopropyl)carbamoyl]-1-methylpyrrol-3-yl]-4-[(5-formamido-1-methylpyrrole-2-carbonyl)amino]-1-methylpyrrole-2-carboxamide
1. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis
2. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
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