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Dynamin inhibitory peptide, myristoylated

Control peptide version of dynamin inhibitory peptide, myristoylated. It is an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Dynamin inhibitory peptide, myristoylated(CAS 251634-22-7)

CAT No: R0848

CAS No:251634-22-7

Synonyms/Alias:251634-22-7;AKOS024456771;Dynamin inhibitory peptide,myristoylated;PD079118;G13348;S-251634-22-7;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C61H107N19O14
M.W/Mr.
1330.6
Sequence
One Letter Code:QVPSRPNRAP
Three Letter Code:myristoyl-Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro-NH2
Labeling Target
GTPase dynamin
Application
Cell-permeable version of dynamin inhibitory peptide , an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization.
Purity
>99 %
Activity
Inhibitor
Solubility
-20 °C
InChI
InChI=1S/C61H107N19O14/c1-5-6-7-8-9-10-11-12-13-14-15-26-48(84)72-39(27-28-46(62)82)52(87)77-49(36(2)3)59(94)80-33-20-25-45(80)56(91)76-42(35-81)54(89)74-40(22-17-30-70-61(67)68)58(93)79-32-19-24-44(79)55(90)75-41(34-47(63)83)53(88)73-38(21-16-29-69-60(65)66)51(86)71-37(4)57(92)78-31-18-23-43(78)50(64)85/h36-45,49,81H,5-35H2,1-4H3,(H2,62,82)(H2,63,83)(H2,64,85)(H,71,86)(H,72,84)(H,73,88)(H,74,89)(H,75,90)(H,76,91)(H,77,87)(H4,65,66,69)(H4,67,68,70)/t37-,38-,39-,40-,41-,42-,43-,44-,45-,49-/m0/s1
InChI Key
IFTSFTVOMZTNME-ZUSDHBTASA-N
Isomeric SMILES
CCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N3CCC[C@H]3C(=O)N
BoilingPoint
N/A
Melting Point
N/A

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