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EBV (LMP1)

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: PPO-H020

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
Application
T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Purity
>70% (HPLC-MS)
Areas of Interest
Infection, Cancer, Hodgkin's lymphoma, Burkitt's lymphoma, Nasopharyngeal carcinoma, Dermatomyositis, Systemic lupus erythematosus, Rheumatoid arthritis, Sj?gren's syndrome, Multiple sclerosis
Size
1 vial containing 15 nmol ( 25μg) per peptide
SwissProt ID
P03230
Format
Freeze dried in amber type glass vial
NumberOfPeptides
94
Organism
Epstein-Barr virus (HHV-4)
Specifications
Peptide scan (15mers with 11 aa overlap)
Protein Length
386
Protein Name
Latent membrane protein 1 (LMP1)
References
1."PepMixTM Peptide Pools for Clinical Applications: T cell therapy for viral infections after hematopoietic stem cell transplant"
Leen et al, Application Note (2012)
2."Expansion of T Cells Targeting Multiple Antigens of Cytomegalovirus, Epstein – Barr Virus and Adenovirus to Provide Broad Antiviral Specificity After Stem Cell Transplantation". Hanley et al., Cytotherapy (2011)
3."Rebound of Residual Plasma Viremia After Initial Decrease Following Addition of Intravenous Immunoglobulin to Effective Antiretroviral Treatment of HIV". Mellberg et al., AIDS Research and Therapy (2011)
4."A Phase II Study Evaluating the Safety and Efficacy of an Adenovirus-LMP1-LMP2 Transduced Dendritic Cell Vaccine in Patients with Advanced Metastatic Nasopharyngeal Carcinoma". Chia et al., Ann. Onc. (2011)

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