Epsilon-V1-2 is a peptidic inhibitor fragment containing diverse residues that support structured folding and ligand-recognition motifs. Researchers use it to examine residue-driven conformational changes, hydrophobic pairing, and protein-interface mapping. The sequence's polarity variations aid biophysical profiling. Its modular design supports mechanistic studies.
CAT No: R2266
CAS No:182683-50-7
Synonyms/Alias:Epsilon-V1-2;182683-50-7;L-alpha-Glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl-L-threonine;(4S)-4-amino-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[(2S)-2-[[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid;CHEMBL3261358;Epsilon-V1-2?;HY-P0154;BDBM50012948;AKOS040754861;DA-63243;MS-31563;CS-0019940;G12953;
Epsilon-V1-2 is a specialized carbohydrate compound recognized for its unique structural characteristics and versatile biochemical properties. As a synthetic oligosaccharide, Epsilon-V1-2 is engineered to offer precise control over glycosidic linkages and branching, making it a valuable tool for research and development across multiple scientific disciplines. Its well-defined molecular architecture allows for reproducible results in experimental settings, supporting advanced studies in carbohydrate chemistry, molecular recognition, and biological interactions. Epsilon-V1-2 is also noted for its stability in aqueous solutions and compatibility with a wide range of analytical techniques, enabling seamless integration into both routine laboratory workflows and cutting-edge research protocols.
Glycoscience Research: Epsilon-V1-2 serves as a critical model substrate in glycoscience research, where it is utilized to investigate the mechanisms of glycosylation, enzyme specificity, and carbohydrate-protein interactions. Researchers employ this compound to elucidate the roles of specific glycosidic bonds in biological recognition processes, facilitating the development of new analytical methods and contributing to a deeper understanding of complex carbohydrate systems. Its defined structure and consistent performance make it an ideal reference material for comparative studies and for validating the activity of glycosyltransferases and glycosidases.
Biomolecular Interaction Studies: In the field of biomolecular interaction studies, Epsilon-V1-2 is frequently used to probe the affinity and specificity of lectins, antibodies, and other carbohydrate-binding proteins. By incorporating this oligosaccharide into binding assays, scientists can map the interaction sites and characterize the binding kinetics of protein-carbohydrate complexes. Such investigations are instrumental in advancing knowledge of cell signaling, immune recognition, and pathogen-host interactions, supporting the rational design of molecular probes and inhibitors that target carbohydrate-mediated processes.
Analytical Method Development: Epsilon-V1-2 plays a pivotal role in the development and validation of analytical techniques for carbohydrate analysis, including chromatography, mass spectrometry, and capillary electrophoresis. As a structurally defined standard, it enables accurate calibration and performance assessment of analytical instruments, ensuring the reliability and reproducibility of quantitative and qualitative measurements. Its use in method optimization helps laboratories achieve high sensitivity and specificity when detecting and quantifying oligosaccharides in complex biological samples.
Material Science and Biomaterials: In material science, Epsilon-V1-2 is explored as a functional building block for the synthesis of carbohydrate-based biomaterials and nanostructures. Its predictable chemical reactivity and compatibility with various modification strategies allow for the creation of tailored surfaces, hydrogels, and scaffolds with specific bioactive properties. Researchers leverage these materials in the development of biosensors, tissue engineering matrices, and drug delivery systems, where controlled carbohydrate presentation is essential for modulating cell behavior and enhancing biocompatibility.
Enzyme Engineering and Screening: Enzyme engineering efforts benefit from the use of Epsilon-V1-2 as a substrate for high-throughput screening of enzyme libraries and directed evolution experiments. Its defined structure enables precise assessment of enzyme activity, substrate specificity, and catalytic efficiency, supporting the identification of novel biocatalysts with desirable properties. By facilitating the rational design and optimization of carbohydrate-active enzymes, this compound accelerates the development of innovative solutions for industrial biotechnology, bioenergy production, and synthetic biology applications. In summary, Epsilon-V1-2 stands out as a multifaceted tool in scientific research, offering unparalleled value in glycoscience, biomolecular interaction studies, analytical method development, material science, and enzyme engineering, thereby advancing both fundamental understanding and technological innovation in carbohydrate-related fields.
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