Gonadorelin

Gonadorelin is a trophic peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released from GnRH neurons within the hypothalamus. The peptide belongs to gonadotropin-releasing hormone family. It constitutes the initial step in the hypothalamic–pituitary–gonadal axis.

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CAT No:10-101-166

CAS No:33515-09-2(net)

Synonyms/Alias:GONADORELIN(2MG);Gonaderelin acetate;GONADORELIN ACETATE;Gonadorelin Acetate/GnRH;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2-amino-2-oxoethyl)amino]-oxomethyl]-1-pyrrolidinyl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methy

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M.F/FormulaC55H75N17O13.C2H4O2
M.W/Mr.1242.36
SequenceThree Letter Code: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 acetate salt
ApplicationGonadorelin is also known as LHRH. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
AppearanceSolid powder
ActivityAgonist
Biological ActivityGonadorelin is a synthetic decapeptide with a structure identical with the natural Gonadotrophin. Releasing Hormone (Gn-RH) in mammalian species.
TargetGonadotropin-releasing hormone receptor
Length10
Shipping ConditionRoom temperature in continental US; may vary elsewhere.
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    Gonadorelin is a trophic peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released from GnRH neurons within the hypothalamus. The peptide belongs to gonadotropin-releasing hormone family. It constitutes the initial step in the hypothalamic–pituitary–gonadal axis.

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