GR 94800

GR94800 is extremely potent and selective NK-2 receptor antagonist.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R1021

CAS No:141636-65-9

Synonyms/Alias:N-Benzoyl-L-alanyl-L-alanyl-D-tryptophyl-L-phenylalanyl-D-prolyl-L-prolyl-L-norleucinamide

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C49H61N9O8
M.W/Mr.
904.08
Sequence
AAWFPPX(Modifications: Ala-1 = N-(Bz)Ala, Trp-3 = D-Trp, Pro-5 = D-Pro, X = Nle with C-terminal amide)
Labeling Target
NK2 Receptors
Purity
>98%
Activity
Antagonist
Source#
Synthetic
InChI
InChI=1S/C49H61N9O8/c1-4-5-21-37(42(50)59)54-47(64)40-23-14-25-57(40)49(66)41-24-15-26-58(41)48(65)39(27-32-16-8-6-9-17-32)56-46(63)38(28-34-29-51-36-22-13-12-20-35(34)36)55-44(61)31(3)52-43(60)30(2)53-45(62)33-18-10-7-11-19-33/h6-13,16-20,22,29-31,37-41,51H,4-5,14-15,21,23-28H2,1-3H3,(H2,50,59)(H,52,60)(H,53,62)(H,54,64)(H,55,61)(H,56,63)/t30-,31-,37-,38+,39-,40-,41+/m0/s1
InChI Key
CWEISCOCKRHHOU-UJYVDGJVSA-N
Isomeric SMILES
CCCC[C@@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H]2CCCN2C(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@@H](CC4=CNC5=CC=CC=C54)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)C6=CC=CC=C6
BoilingPoint
1310.4ºC at 760 mmHg
Melting Point
N/A

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