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Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.
| CAT# | R1887 |
| Explanation | Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. |
| Synonyms/Alias | GRGDS |
| Chemical Name | (3S)-3-[[2-[[(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-4-oxobutanoic acid |
| M.F/Formula | C17H30N8O9 |
| M.W/Mr. | 490.5 |
| Sequence | One Letter Code: GRGDS Three Letter Code: H-Gly-Arg-Gly-Asp-Ser-OH |
| Appearance | White to off-white lyophilized solid |
| Purity | ≥97% by HPLC |
| Long-term Storage Conditions | DMSO : 100 mg/mL (ultrasonic);H2O : 33.33 mg/mL (ultrasonic) | Shipping Condition | RT, or blue ice upon request. | InChI | InChI=1S/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1 | InChI Key | RGNVSYKVCGAEHK-GUBZILKMSA-N | Canonical SMILES | C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)NC(=O)CN)CN=C(N)N | Isomeric SMILES | C(C[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)O)NC(=O)CN)CN=C(N)N |
| CAT# | Product Name | M.W | Molecular Formula | Inquiry |
|---|---|---|---|---|
| R1442 | IGF-I 24-41 | Inquiry | ||
| R1421 | HIF-1 alpha 556-574 | Inquiry | ||
| R1731 | Tuftsin diacetate | Inquiry | ||
| R1532 | Neurokinin A(4-10) | Inquiry | ||
| R1704 | TAK-448 acetate | Inquiry |
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