Hexapeptide-42

Hexapeptide-42 is a synthetic peptide composed of six amino acids, designed for use as an active ingredient in cosmetic formulations. Recognized for its role in supporting the skin's barrier function, Hexapeptide-42 is suitable for inclusion in products targeting skin conditioning and maintenance. Its stability and compatibility with a range of formulation types make it a versatile option for modern skincare applications within global regulatory frameworks.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1671

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C25H46N10O8
M.W/Mr.
646.96
Functions
Hexapeptide-42 is an anti-aging peptide designed to adaptively energize skin or help protect mitohondrial DNA, based on the needs of the mitochondria.

Mechanism of Action (MOA)

Hexapeptide-42 is a synthetic signal peptide designed to interact with cellular communication pathways in the epidermis. By mimicking naturally occurring peptide sequences, it may modulate the activity of keratinocytes through targeted engagement with specific cell surface receptors. This interaction can influence intracellular signaling cascades, supporting the skin's physiological processes involved in maintaining optimal barrier function and homeostasis. Hexapeptide-42 is suitable for use in formulations targeting improved skin conditioning.

Hexapeptide-42 can be incorporated into various cosmetic formulations to support advanced skincare product development.

- Suitable for use in facial serums and emulsions
- Can be added to lightweight lotions and creams
- Compatible with gel-based and aqueous systems
- Appropriate for inclusion in sheet masks and leave-on treatments
- May be blended into eye contour products
- Recommended for use in daily skincare routines

INCIName
HEXAPEPTIDE-42

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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

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