hLF1-11

hLF1-11 is a synthetic peptide corresponding to the first 11 N-terminal amino acids of human lactoferrin (hLF1-11) with potential antimicrobial activity. hLF1-11 is effective against a variety of bacteria and fungi, including multidrug-resistant (MDR) strains of Acinetobacter baumannii and Staphylococcus aureus, and fluconazole-resistant Candida albicans strains.

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CAT#10-101-148
M.F/FormulaC56H95N25O14S1
M.W/Mr.1374.6
SequenceGRRRRSVQWCA
ApplicationhLF1-11 is used as broad spectrum antmicrobial prophylaxis in HSCT patients.
Biological ActivityHuman lactoferrin 1-11 (hLF1-11) is a lactoferrin derivative being developed for the treatment of bacterial and fungal infections in HSCT recipients. hLF1–11 (GRRRRSVQWCA) is an antimicrobial peptide (AMP) with high activity against methicillin-resistant Staphylococcus aureus (MRSA), the most prevalent species in implant-associated infection.
Areas of InterestInfection
TargetAntimicrobial
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