hLF1-11 is a synthetic peptide corresponding to the first 11 N-terminal amino acids of human lactoferrin (hLF1-11) with potential antimicrobial activity. hLF1-11 is effective against a variety of bacteria and fungi, including multidrug-resistant (MDR) strains of Acinetobacter baumannii and Staphylococcus aureus, and fluconazole-resistant Candida albicans strains.
CAT# | 10-101-148 |
M.F/Formula | C56H95N25O14S1 |
M.W/Mr. | 1374.6 |
Sequence | GRRRRSVQWCA |
Application | hLF1-11 is used as broad spectrum antmicrobial prophylaxis in HSCT patients. |
Biological Activity | Human lactoferrin 1-11 (hLF1-11) is a lactoferrin derivative being developed for the treatment of bacterial and fungal infections in HSCT recipients. hLF1–11 (GRRRRSVQWCA) is an antimicrobial peptide (AMP) with high activity against methicillin-resistant Staphylococcus aureus (MRSA), the most prevalent species in implant-associated infection. |
Areas of Interest | Infection |
Target | Antimicrobial |
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