L-CITRULLINE (4,4,5,5-D4) is an isotopically labeled, non-proteinogenic amino acid derivative of citrulline featuring a ureido side chain attached to the α-amino acid backbone. The molecule contains an α-amino group and a carboxyl group, with the ureido functionality bearing two carbonyl-linked nitrogens, while deuterium incorporation at the 4,4,5,5 positions of the side chain provides a defined D4 isotopic labeling pattern. It is used in isotopic tracing, quantitative LC-MS or NMR analytical method development, and structure-activity or biochemical studies where tracking or distinguishing citrulline-derived species based on mass or isotopic signatures is required.
CAT No: L-Iso-0162
1. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis
4. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
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